MedPath

Human interferon beta

Generic Name
Human interferon beta
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
74899-71-1
Unique Ingredient Identifier
V9GU1EM8SF
Background

Human interferon beta is a polypeptide used in the management of relapsing forms of Multiple Sclerosis (MS), and was initially approved by the FDA in 1992. Multiple Sclerosis is a devastating neurodegenerative disease that is usually progressive and significantly debilitating with a profound impact on the quality of life.

Interferon beta is currently being studied as a possible treatment for COVID-19, which results from infection with the novel 2019 SARS-CoV-2 virus. Interferon-beta has been used in the past in clinical studies with other coronaviruses due to its demonstrated activity against the virus causing Middle Eastern Respiratory Syndrome (MERS). It is therefore a potential drug candidate for SARS-CoV-2 based on viral genetic similarity.

Indication

This drug is indicated to treat relapsing forms of Multiple Sclerosis (MS) in adults, which includes clinically isolated syndrome, relapsing-remitting disease, as well as active secondary progressive disease.

Associated Conditions
Relapsing Remitting Multiple Sclerosis (RRMS)
Associated Therapies
-

Synairgen backer ready to pump £18-£19 million into phase II trial

Synairgen PLC plans to raise up to £25 million to fund SNG001 development, an inhaled interferon beta treatment for respiratory viral infections. TFG Asset Management backs the initiative, acquiring shares at a 47% discount. The funds will support a phase II trial in mechanically ventilated patients, aiming to reduce mortality rates. The investment also positions SNG001 for potential partnerships. If fundraising fails to meet the £2.9 million minimum, Synairgen may delist from AIM.
telegrafi.com
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Three professors become 'overnight' millionaires, after a 'major breakthrough' in medicine

Three university professors, Ratko Djukanovic, Stephen Holgate, and Donna Davies, became millionaires after their company, Synairgen, achieved a 3,000% share increase due to a successful COVID-19 drug trial. The drug, SNG001, administered via inhaler, showed significant recovery and reduced severe illness rates in patients.
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