Overview
Neratinib was approved in July 2017 for use as an extended adjuvant therapy in Human Epidermal Growth Factor Receptor 2 (HER2) positive breast cancer. Approval was granted to Puma Biotechnology Inc. for the tradename Nerlynx. Neratinib is currently under investigation for use in many other forms of cancer.
Indication
For use as an extended adjuvant treatment in adult patients with early stage HER2-overexpressed/amplified breast cancer, to follow adjuvant trastuzumab-based therapy [FDA Label].
Associated Conditions
- Breast Cancer
Clinical Trials
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Title | Posted | Study ID | Phase | Status | Sponsor |
|---|---|---|---|---|---|
2021/12/13 | Phase 2 | Not yet recruiting | |||
2021/05/25 | Phase 2 | Withdrawn | |||
2021/05/14 | Phase 2 | Recruiting | Ruth O'Regan | ||
2021/04/23 | Phase 2 | Withdrawn | |||
2021/03/04 | Phase 2 | Withdrawn | |||
2020/08/06 | Phase 1 | Active, not recruiting | |||
2020/07/07 | Phase 2 | Terminated | SOLTI Breast Cancer Research Group | ||
2020/05/14 | N/A | Active, not recruiting | |||
2020/05/05 | Phase 2 | Active, not recruiting | Scott R. Plotkin, MD, PhD | ||
2020/04/29 | Phase 2 | Completed |
FDA Drug Approvals
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UK EMC Drug Information
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