Desmopressin
- Generic Name
- Desmopressin
- Brand Names
- Ddavp, Nocdurna, Octostim
- Drug Type
- Small Molecule
- Chemical Formula
- C46H64N14O12S2
- CAS Number
- 16679-58-6
- Unique Ingredient Identifier
- ENR1LLB0FP
- Background
Desmopressin (dDAVP), a synthetic analogue of 8-arginine vasopressin (ADH), is an antidiuretic peptide drug modified by deamination of 1-cysteine and substitution of 8-L-arginine by 8-D-arginine. ADH is an endogenous pituitary hormone that has a crucial role in the control of the water content in the body. Upon release from the stimulation of increased plasm...
- Indication
1.治疗中枢性尿崩症，可减少尿量、提高尿渗透压、降低血浆渗透压；
2.用于尿崩症的诊断和鉴别诊断；
3.用于治疗夜间遗尿症（六岁或以上的患者）；
4.部分类型（甲型血友病和Ⅰ型血管性假血友病）的血友病及其他出血性疾病。
- Associated Conditions
- Bleeding, Hypothalamic Injury-induced Obesity (HIO), Nocturia, Nocturnal Polyuria, Polydipsia, Polyuria, Primary Nocturnal Enuresis
- Associated Therapies
- -
Desmopressin for Bedwetting in Children With SCD
- First Posted Date
- 2020-06-09
- Last Posted Date
- 2024-05-07
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 8
- Registration Number
- NCT04420585
- Locations
- 🇺🇸
Children's Hospital at Montefiore, Bronx, New York, United States
Specified Drug Use-results Survey (Long-term Use) on MINIRINMELT® OD Tablet (Nocturia)
- First Posted Date
- 2020-04-01
- Last Posted Date
- 2024-12-20
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 1087
- Registration Number
- NCT04329975
- Locations
- 🇯🇵
Survey Site (there may be other sites in this country), Tokyo, Japan
Safety and Tolerability Analysis of Combining Desmopressin With Docetaxel for the Treatment of Castration-Resistant Prostate Cancer
- First Posted Date
- 2019-10-02
- Last Posted Date
- 2019-10-02
- Lead Sponsor
- Sunnybrook Health Sciences Centre
- Target Recruit Count
- 10
- Registration Number
- NCT04113005
A SAD/MAD Study of Safety, Tolerability and Pharmacologic Activity of BT200 in Normal Volunteers
- Conditions
- Interventions
- First Posted Date
- 2019-09-25
- Last Posted Date
- 2024-03-18
- Lead Sponsor
- Band Therapeutics
- Target Recruit Count
- 112
- Registration Number
- NCT04103034
- Locations
- 🇦🇹
Medical University of Vienna, Vienna, Austria
Study on Chinese and Western Medicine in MNE Children
- Conditions
- Interventions
- First Posted Date
- 2018-11-07
- Last Posted Date
- 2021-03-11
- Lead Sponsor
- Children's Hospital of Fudan University
- Target Recruit Count
- 400
- Registration Number
- NCT03733873
- Locations
- 🇨🇳
Children's hospital of Fudan university, Shanghai, Shanghai, China
To Evaluate the Renal Tubular Function Pre and Post Nephrectomy in Living Donors
- First Posted Date
- 2018-09-18
- Last Posted Date
- 2019-05-20
- Lead Sponsor
- University of Kansas Medical Center
- Registration Number
- NCT03676361
- Locations
- 🇺🇸
University of Kansas Medical Center, Kansas City, Kansas, United States
The Effect of Selecting Treatment With Desmopressin or Alarm to Children With Enuresis Based on Home Recordings.
- Conditions
- Interventions
- First Posted Date
- 2018-01-03
- Last Posted Date
- 2023-08-02
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 324
- Registration Number
- NCT03389412
- Locations
- 🇩🇰
Aalborg University Hospital, Aalborg, Jylland, Denmark
🇨🇳First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, China
🇧🇪Ghent University Hospital, Ghent, Belgium
Effects of Prophylactic Desmopressin on Blood Coagulation Parameters in Heart Valve Surgery
- Conditions
- Interventions
- First Posted Date
- 2017-11-17
- Last Posted Date
- 2017-11-17
- Lead Sponsor
- Instituto do Coracao
- Target Recruit Count
- 108
- Registration Number
- NCT03343418
- Locations
- 🇧🇷
Incor - Heart Institute - University of Sao Paulo, Sao Paulo, Brazil
A Trial to Investigate Efficacy, Safety and Tolerability of FE 201836 for Nocturia Due to Nocturnal Polyuria in Adults
- Conditions
- Interventions
- First Posted Date
- 2017-06-28
- Last Posted Date
- 2022-03-02
- Lead Sponsor
- Ferring Pharmaceuticals
- Target Recruit Count
- 302
- Registration Number
- NCT03201419
- Locations
- 🇺🇸
Advanced Rx Clinical Research Group, Inc., Westminster, California, United States
🇺🇸MCA Research - Partner, Houston, Texas, United States
🇺🇸Doctors Research Institute Corporation, Miami, Florida, United States
DDAVP vs. Exercise in Patients With Mild Hemophilia A
- First Posted Date
- 2017-05-02
- Last Posted Date
- 2017-12-04
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 30
- Registration Number
- NCT03136003
- Locations
- 🇨🇦
St. Michael's Hospital, Toronto, Ontario, Canada
🇨🇦The Hospital for Sick Children, Toronto, Ontario, Canada
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.