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Solabegron

Generic Name
Solabegron
Drug Type
Small Molecule
Chemical Formula
C23H23ClN2O3
CAS Number
252920-94-8
Unique Ingredient Identifier
55P6YH9O6N
Background

Solabegron (GW-427,353) is a selective β3 adrenoceptor agonist being developed for the treatment of overactive bladder and irritable bowel syndrome.

Indication

Investigated for use/treatment in diabetes mellitus type 2, irritable bowel syndrome (IBS), and urinary incontinence.

A Study To Investigate The Effect Of Solabegron (GW427353) On Gastrointestinal Transit In Healthy Volunteers

Phase 1
Completed
Conditions
Irritable Bowel Syndrome (IBS)
First Posted Date
2006-11-20
Last Posted Date
2008-10-16
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
36
Registration Number
NCT00401479
Locations
🇺🇸

GSK Investigational Site, Rochester, Minnesota, United States

A Study To Investigate GW427353 In Subjects With Irritable Bowel Syndrome (IBS)

Phase 2
Completed
Conditions
Irritable Bowel Syndrome (IBS)
First Posted Date
2006-10-31
Last Posted Date
2009-05-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
100
Registration Number
NCT00394186
Locations
🇩🇪

GSK Investigational Site, Hamburg, Germany

Dose Ranging Study Of Solabegron Versus Placebo In Female Patients With Overactive Bladder Symptoms

Phase 2
Completed
Conditions
Overactive Bladder
First Posted Date
2006-06-23
Last Posted Date
2009-05-18
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
240
Registration Number
NCT00343486
Locations
🇨🇳

GSK Investigational Site, Taipei, Taiwan

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