Progesterone

Generic Name
Progesterone
Brand Names
Bijuva, Crinone, Endometrin, Prochieve, Prometrium
Drug Type
Small Molecule
Chemical Formula
C21H30O2
CAS Number
57-83-0
Unique Ingredient Identifier
4G7DS2Q64Y
Background

Progesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss . Progesterone is used in various contraceptive preparations to prev...

Indication

Gelatinized capsules

The gelatinized capsules are indicated for use in the prevention of endometrial hyperplasia in non-hysterectomized postmenopausal women who are receiving conjugated estrogens tablets. They are also indicated for use in secondary amenorrhea .

Vaginal gel
...

Associated Conditions
Abnormal Uterine Bleeding, Amenorrhea, Endometrial hyperplasia caused by conjugated estrogen, Moderate to Severe Vasomotor Symptoms, Pregnancy, Secondary Amenorrhea, Recurrent spontaneous preterm birth
Associated Therapies
Assisted Reproductive Technology therapy

Natural Cycle Versus Hormone Replacement Therapy Cycle for a Frozen-thawed Embryo Transfer in PGT Patients

First Posted Date
2019-06-06
Last Posted Date
2024-10-09
Lead Sponsor
CRG UZ Brussel
Target Recruit Count
362
Registration Number
NCT03976544
Locations
🇧🇪

Centre for Reproductive Medicine UZ Brussel, Brussels, Belgium

Progesterone Supplementation in Threatened Abortion

First Posted Date
2019-04-29
Last Posted Date
2023-07-18
Lead Sponsor
Tanta University
Target Recruit Count
190
Registration Number
NCT03930212
Locations
🇪🇬

Ayman Shehata Dawood, Tanta, Egypt

Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2019-02-28
Last Posted Date
2024-03-12
Lead Sponsor
Merck KGaA, Darmstadt, Germany
Target Recruit Count
172
Registration Number
NCT03858049
Locations
🇨🇳

Peking University Third Hospital, Beijing, China

Reducing the Risk of Drug-Induced QT Interval Lengthening in Women

First Posted Date
2019-02-08
Last Posted Date
2024-05-31
Lead Sponsor
Indiana University
Target Recruit Count
16
Registration Number
NCT03834883
Locations
🇺🇸

Indiana University, Indianapolis, Indiana, United States

Blocking Mifepristone Action With Progesterone

First Posted Date
2018-12-13
Last Posted Date
2020-01-22
Lead Sponsor
University of California, Davis
Target Recruit Count
12
Registration Number
NCT03774745
Locations
🇺🇸

Planned Parenthood Mar Monte, Sacramento, California, United States

🇺🇸

Family Planning Associates, Sacramento, California, United States

🇺🇸

University of California, Davis, Sacramento, California, United States

Impact of Progesterone on Stress Reactivity and Cannabis Use

Phase 2
Completed
Conditions
Interventions
First Posted Date
2018-11-05
Last Posted Date
2023-09-28
Lead Sponsor
Medical University of South Carolina
Target Recruit Count
148
Registration Number
NCT03729869
Locations
🇺🇸

Medical University of South Carolina, Charleston, South Carolina, United States

Clinical Study on Endometrial Receptivity

First Posted Date
2018-09-27
Last Posted Date
2018-09-27
Lead Sponsor
Peking Union Medical College Hospital
Target Recruit Count
35
Registration Number
NCT03687021
Locations
🇨🇳

Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing, Beijing, China

Natural Versus Artificial Cycle for Frozen-Thawed Embryo Transfer

First Posted Date
2018-08-22
Last Posted Date
2024-06-28
Lead Sponsor
Universitaire Ziekenhuizen KU Leuven
Target Recruit Count
554
Registration Number
NCT03642665
Locations
🇧🇪

UZ Leuven, Leuven, Belgium

Verify the Safety and Effectiveness of the Cerclage Pessary in Prevention and Treatment of High-risk Preterm Pregnancy

Not Applicable
Not yet recruiting
Conditions
Interventions
First Posted Date
2018-08-17
Last Posted Date
2023-11-18
Lead Sponsor
QH Medical Technology Ltd.
Target Recruit Count
300
Registration Number
NCT03637062
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