Follitropin

Generic Name
Follitropin
Brand Names
Bemfola, Follistim, Gonal F, Gonal-F, Menopur, Ovaleap, Pergoveris, Puregon, GONAL-f, Rekovelle
Drug Type
Biotech
Chemical Formula
-
CAS Number
146479-72-3
Unique Ingredient Identifier
2M2GGL7HUP
Background

Follitropin is a human follicle stimulating hormone (FSH) preparation of recombinant DNA origin, which consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glyco...

Indication

In women having been diagnosed with primary ovarian failure, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. In men with hypogonadotrophic hypogonadism, it is used to induce spermatogenesis. Follitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use...

Associated Conditions
-
Associated Therapies
Assisted Reproductive Technology therapy, Controlled Ovarian Stimulation

An Exploratory Study to Investigate the Effect of FE 999302 When Given Together With Follitropin Delta at Different Time Intervals During Controlled Ovarian Stimulation.

First Posted Date
2024-07-22
Last Posted Date
2024-11-26
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
200
Registration Number
NCT06511791
Locations
🇪🇸

Ferring Investigational Site, Valencia, Spain

An Exploratory Study to Investigate the Effect of FE 999302 When Given Together With Follitropin Delta During Controlled Ovarian Stimulation

First Posted Date
2024-06-20
Last Posted Date
2024-12-20
Lead Sponsor
Ferring Pharmaceuticals
Target Recruit Count
600
Registration Number
NCT06466486
Locations
🇪🇸

Ferring Investigational Site, Valencia, Spain

Use of Pulsatile Intravenous FSH to Mitigate Reprometabolic Syndrome

Phase 1
Recruiting
Conditions
Interventions
First Posted Date
2024-05-16
Last Posted Date
2024-11-27
Lead Sponsor
University of Colorado, Denver
Target Recruit Count
5
Registration Number
NCT06414096
Locations
🇺🇸

University of Colorado Anschutz Medical Campus, Aurora, Colorado, United States

Retrospective Study of High Dose Follitropin Delta in a Mixed Protocol With Human Chorionic Gonadotropin

Active, not recruiting
Conditions
Interventions
First Posted Date
2023-05-24
Last Posted Date
2023-10-31
Lead Sponsor
Clinique Ovo
Target Recruit Count
150
Registration Number
NCT05873725
Locations
🇨🇦

Clinique Ovo, Montreal, Quebec, Canada

Continuous Double Ovarian Stimulation.

First Posted Date
2023-04-18
Last Posted Date
2023-04-18
Lead Sponsor
Instituto Bernabeu
Target Recruit Count
30
Registration Number
NCT05815719
Locations
🇪🇸

Instituto Bernabeu, Alicante, Spain

Real-world Evidence on Follitropin Delta Individual Dosing

Recruiting
Conditions
Interventions
First Posted Date
2021-12-30
Last Posted Date
2024-12-05
Lead Sponsor
University of Luebeck
Target Recruit Count
850
Registration Number
NCT05173597
Locations
🇩🇪

University of Luebeck, Luebeck, Schleswig-Holstein, Germany

Cumulative Pregnancy Rate With Lower and Higher Gonadotropin Dose During IVF Among Poor Responders

First Posted Date
2021-11-02
Last Posted Date
2024-12-13
Lead Sponsor
Peter Kovacs MD
Target Recruit Count
190
Registration Number
NCT05103228
Locations
🇭🇺

Dunamenti REK Reprodukciós Központ, Budapest, Hungary

Estradiol and Progesterone Levels Following Frozen Embryo Transfer

First Posted Date
2021-08-09
Last Posted Date
2024-05-14
Lead Sponsor
Copenhagen University Hospital at Herlev
Target Recruit Count
300
Registration Number
NCT04997525
Locations
🇩🇰

Herlev University Hospital, Herlev, Denmark

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