Oxygen

Generic Name: Oxygen

Brand Names: Alnox, Ez-OX, Heliox, Oxygen, Southern Medical

Drug Type: Small Molecule

Chemical Formula: O_₂

CAS Number: 7782-44-7

Unique Ingredient Identifier: S88TT14065

Background: Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased c...

Indication: Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia to reduce t...

Associated Conditions: Anemia, Cancer, Hypoxemia, Hypoxia, Migraine, Polycythemia, Pulmonary Hypertension (PH), Respiratory Disorders, Sleep Apnea

Associated Therapies: -

Clinical Trials

Intracervical Balloon Placement With Nitrous Oxide Administration

Phase 3

Recruiting

Conditions: Induced; Birth
Labor Pain

Interventions: Drug: Nitrous oxide
Drug: Oxygen

First Posted Date: 2024-07-12

Last Posted Date: 2024-07-12

Lead Sponsor: Maimonides Medical Center

Target Recruit Count: 162

Registration Number: NCT06498908

Locations: 🇺🇸
Maimonides Medical Center OB/GYN, Brooklyn, New York, United States

Heliox on the Work of Breathing in Adult Patients With Lower Airway Stenosis

Active, not recruiting

Conditions: Airway Obstruction

Interventions: Drug: Heliox
Drug: Oxygen

First Posted Date: 2024-06-13

Last Posted Date: 2024-06-13

Lead Sponsor: Hospital Universitario 12 de Octubre

Target Recruit Count: 18

Registration Number: NCT06457399

Locations: 🇪🇸
Marta Corral Blanco, Madrid, Spain

A Feasibility Study of Supplemental Oxygen to Improve Pulmonary Hypertension in People With Intradialytic Hypoxemia

Phase 1

Not yet recruiting

Conditions: Pulmonary Hypertension

Interventions: Drug: Oxygen
Drug: Room air

First Posted Date: 2024-03-25

Last Posted Date: 2024-10-28

Lead Sponsor: Duke University

Target Recruit Count: 10

Registration Number: NCT06327373

Locations: 🇺🇸
Davita Durham East, Durham, North Carolina, United States
🇺🇸
Davita Research Triangle Park, Durham, North Carolina, United States
🇺🇸
Davita Durham Downtown, Durham, North Carolina, United States

and more 8 locations

Oxygen as an Acute Treatment in Alternating Hemiplegia of Childhood

Phase 2

Not yet recruiting

Conditions: Alternating Hemiplegia of Childhood

Interventions: Drug: Oxygen
Drug: Placebo

First Posted Date: 2024-02-08

Last Posted Date: 2024-04-12

Lead Sponsor: Assistance Publique - Hôpitaux de Paris

Target Recruit Count: 24

Registration Number: NCT06248645

Locations: 🇫🇷
HCL LYON, Lyon, France
🇫🇷
Hôpital Pitié Salpêtrière, Paris, France

Oxygen Therapy in Children and Adolescents With Down Syndrome and Obstructive Sleep Apnea

Phase 2

Recruiting

Conditions: Down Syndrome
Obstructive Sleep Apnea

Interventions: Drug: Oxygen

First Posted Date: 2023-09-21

Last Posted Date: 2024-02-22

Lead Sponsor: Brigham and Women's Hospital

Target Recruit Count: 230

Registration Number: NCT06043440

Locations: 🇺🇸
Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, United States
🇺🇸
Children's Hospital of Los Angeles, Los Angeles, California, United States
🇺🇸
Seattle Children's Hospital, Seattle, Washington, United States

and more 4 locations

Cerebral Nitrosative/Oxidative Stress in Aneurysmal Subarachnoid Haemorrhage

Terminated

Conditions: Subarachnoid Hemorrhage, Aneurysmal

Interventions: Drug: Oxygen

First Posted Date: 2023-01-17

Last Posted Date: 2024-03-19

Lead Sponsor: Rigshospitalet, Denmark

Target Recruit Count: 3

Registration Number: NCT05686265

Locations: 🇩🇰
Rigshospitalet, Copenhagen, Denmark

Oxygen Targets in Acute Heart Failure With Pulmonary Congestion

Phase 2

Recruiting

Conditions: Pulmonary Congestion
Acute Heart Failure
Hypoxemia

Interventions: Drug: Oxygen

First Posted Date: 2022-11-14

Last Posted Date: 2024-02-16

Lead Sponsor: Copenhagen University Hospital, Hvidovre

Target Recruit Count: 122

Registration Number: NCT05613218

Locations: 🇩🇰
Bispebjerg Hospital, Copenhagen, Denmark
🇩🇰
Amager-Hvidovre Hospital, Copenhagen, Denmark

Oxygen Reserve Index and Prevention of Hyperoxemia

Phase 4

Completed

Conditions: Oxygen Reserve Index
Hyperoxia
Hyperoxemia
Fraction of Inspired Oxygen

Interventions: Drug: Oxygen
Device: Masimo Root Radical 7

First Posted Date: 2022-08-17

Last Posted Date: 2023-05-22

Lead Sponsor: Baskent University Ankara Hospital

Target Recruit Count: 108

Registration Number: NCT05505032

Locations: 🇹🇷
Baskent University Ankara Hospital, Ankara, Cankaya, Turkey

Intermittent Versus Continuous Surface O2 During HMP of DCD Kidneys

Phase 3

Recruiting

Conditions: Delayed Graft Function
Ischemia Reperfusion Injury
Kidney Transplant; Complications
Mitochondrial

Interventions: Drug: Oxygen

First Posted Date: 2022-06-24

Last Posted Date: 2024-05-23

Lead Sponsor: Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Target Recruit Count: 60

Registration Number: NCT05430620

Locations: 🇧🇪
Cliniques Universitaires Saint-Luc, Brussel, Woluwé-Saint-Lambert, Belgium

Effect of Using Oxygen on the Diaper Dermatitis in Infants

Not Applicable

Completed

Conditions: Diaper Dermatitis
Diaper Rash

Interventions: Drug: Oxygen

First Posted Date: 2022-06-22

Last Posted Date: 2024-10-18

Lead Sponsor: Istanbul University - Cerrahpasa (IUC)

Target Recruit Count: 103

Registration Number: NCT05427760

Locations: 🇹🇷
Istanbul University Cerrahpasa, Istanbul, Turkey

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