Oxygen

Generic Name
Oxygen
Brand Names
Alnox, Ez-OX, Heliox, Oxygen, Southern Medical
Drug Type
Small Molecule
Chemical Formula
O2
CAS Number
7782-44-7
Unique Ingredient Identifier
S88TT14065
Background

Oxygen is an element displayed by the symbol O, and atomic number 8. It is an essential element for human survival. Decreased oxygen levels may be treated with medical oxygen therapy. Treatment with oxygen serves to increase blood oxygen levels and also exerts a secondary effect of decreasing blood flow resistance in the diseased lung, leading to decreased cardiovascular workload in an attempt to oxygenate the lungs. Oxygen therapy is used to treat emphysema, pneumonia, some heart disorders (congestive heart failure), some disorders that cause increased pulmonary artery pressure, and any disease that impairs the body's ability to take up and use gaseous oxygen. Higher level of oxygen than ambient air (hyperoxia) can be introduced under normobaric or hyperbaric conditions.

Indication

Oxygen therapy in clinical settings is used across diverse specialties, including various types of anoxia, hypoxia or dyspnea and any other disease states and conditions that reduce the efficiency of gas exchange and oxygen consumption such as respiratory illnesses, trauma, poisonings and drug overdoses. Oxygen therapy tries to achieve hyperoxia to reduce the extent of hypoxia-induced tissue damage and malfunction.

Associated Conditions
Anemia, Cancer, Hypoxemia, Hypoxia, Migraine, Polycythemia, Pulmonary Hypertension (PH), Respiratory Disorders, Sleep Apnea
Associated Therapies
-

Application of Nasal Cannula With Oxygen Versus Air During Eye Surgery Under Local Anaesthetic

Phase 1
Completed
Conditions
Interventions
First Posted Date
2010-07-07
Last Posted Date
2011-08-17
Lead Sponsor
University of Malaya
Target Recruit Count
100
Registration Number
NCT01157624
Locations
🇲🇾

University Malaya Medical Center, Kuala Lumpur, Federal Teritory, Malaysia

A Novel Method of Preoxygenation Using a Bain Circuit

Phase 4
Conditions
Interventions
First Posted Date
2009-08-13
Last Posted Date
2009-08-13
Lead Sponsor
National Health Service, United Kingdom
Target Recruit Count
40
Registration Number
NCT00958178
Locations
🇬🇧

Victoria Infirmary, Glasgow, United Kingdom

The Interest of the Nitrous Oxide During Intravesical Injection of Botulinum Toxin A

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-07-29
Last Posted Date
2014-11-06
Lead Sponsor
Assistance Publique - Hôpitaux de Paris
Target Recruit Count
33
Registration Number
NCT00948103
Locations
🇫🇷

Hopital Raymond Poincaré, Garches, France

Measurement of Retinal Blood Flow, Retinal Oxygenation and Retinal Oxygen Extraction in Healthy Subjects During Normoxia and Systemic Hyperoxia

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2009-06-05
Last Posted Date
2017-03-10
Lead Sponsor
Medical University of Vienna
Target Recruit Count
48
Registration Number
NCT00914407
Locations
🇦🇹

Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria

Heliox in Experimental Upper Airway Obstruction

Phase 1
Completed
Conditions
Interventions
First Posted Date
2008-11-11
Last Posted Date
2008-11-21
Lead Sponsor
University of Witten/Herdecke
Target Recruit Count
44
Registration Number
NCT00788788
Locations
🇩🇪

HELIOS-Klinikum / University of Witten/Herdecke, Wuppertal, NRW, Germany

Respiratory Effects of Perioperative Oxygen During General Anaesthesia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2008-03-18
Last Posted Date
2009-01-12
Lead Sponsor
University of Copenhagen
Target Recruit Count
35
Registration Number
NCT00637936

Comparison of Inhaled Nitric Oxide and Oxygen in Participants Reactivity During Acute Pulmonary Vasodilator Testing

First Posted Date
2008-02-29
Last Posted Date
2019-12-20
Lead Sponsor
Mallinckrodt
Target Recruit Count
136
Registration Number
NCT00626028
Locations
🇺🇸

Columbus Children's Hospital, Columbus, Ohio, United States

🇫🇷

CHU Timone - Département de cardiologie, Marseille, France

🇪🇸

Hospital Gregorio Maranon, Madrid, Spain

and more 15 locations

Consequences of Nocturnal and Daytime Hypoxemia in COPD

Not Applicable
Terminated
Conditions
Interventions
First Posted Date
2007-10-22
Last Posted Date
2015-12-16
Lead Sponsor
Northwell Health
Target Recruit Count
20
Registration Number
NCT00547456
Locations
🇺🇸

North Shore LIJ Health System, New Hyde Park, New York, United States

Gas Usage for Those With COPD Who Experience Low Oxygen Levels During Activities Only

Not Applicable
Completed
Conditions
First Posted Date
2007-10-18
Last Posted Date
2024-04-30
Lead Sponsor
West Park Healthcare Centre
Target Recruit Count
27
Registration Number
NCT00546299

Oxygen Therapy in Schizophrenia

Phase 3
Conditions
First Posted Date
2007-09-06
Last Posted Date
2008-05-28
Lead Sponsor
Beersheva Mental Health Center
Target Recruit Count
20
Registration Number
NCT00525863
Locations
🇮🇱

Beersheva Mental Health Center, Beersheva, Israel

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