Salbutamol
- Generic Name
- Salbutamol
- Brand Names
- Airomir, Airsupra, Combivent, Proair, Proventil, Ventolin
- Drug Type
- Small Molecule
- Chemical Formula
- C13H21NO3
- CAS Number
- 18559-94-9
- Unique Ingredient Identifier
- QF8SVZ843E
- Background
Salbutamol is a short-acting, selective beta2-adrenergic receptor agonist used in the treatment of asthma and COPD. It is 29 times more selective for beta2 receptors than beta1 receptors giving it higher specificity for pulmonary beta receptors versus beta1-adrenergic receptors located in the heart. Salbutamol is formulated as a racemic mixture of the R- and...
- Indication
Salbutamol is indicated for (i) the symptomatic relief and prevention of bronchospasm due to bronchial asthma, chronic bronchitis, reversible obstructive airway disease, and other chronic bronchopulmonary disorders in which bronchospasm is a complicating factor, and/or (ii) the acute prophylaxis against exercise-induced bronchospasm and other stimuli known t...
- Associated Conditions
- Asthma, Asthmatic Bronchitis, Bronchial Asthma, Bronchoconstriction, Bronchospasm, Chronic Asthma, Chronic Bronchitis, Cough, Emphysema, Exacerbation of asthma, Exercise-Induced Bronchospasm, Hyperkalemia, Wheezing, Excess mucus or phlegm
- Associated Therapies
- Airway secretion clearance therapy, Bronchodilation
Acute Effect of Salbutamol on Heart Rate and Blood Pressure During Exercise in Patients With Moderate or Severe Asthma and Healthy Subjects
- First Posted Date
- 2017-02-07
- Last Posted Date
- 2017-02-07
- Lead Sponsor
- Universidade Ibirapuera
- Target Recruit Count
- 15
- Registration Number
- NCT03044938
- Locations
- 🇧🇷
Jaqueline Ribas de Melo, Sao Paulo, São Paulo, Brazil
Beta2-mimetic and Central Nervous System
- Conditions
- Interventions
- First Posted Date
- 2016-10-05
- Last Posted Date
- 2017-10-02
- Lead Sponsor
- University Hospital, Grenoble
- Target Recruit Count
- 15
- Registration Number
- NCT02925130
- Locations
- 🇫🇷
Grenoble University Hospital, Grenoble, France
The Cardiopulmonary Effect of Inhaled Beta-2-agonists on Adult Patients Born With Ventricular Septum Defects.
- Conditions
- Interventions
- First Posted Date
- 2016-09-26
- Last Posted Date
- 2018-07-05
- Lead Sponsor
- University of Aarhus
- Target Recruit Count
- 96
- Registration Number
- NCT02914652
- Locations
- 🇩🇰
Dept. of Cardiothoracic and Vascular Surgery, Aarhus, Denmark
Inhaled Beta-adrenergic Agonists to Treat Pulmonary Vascular Disease in Heart Failure With Preserved EF (BEAT HFpEF): A Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2016-08-31
- Last Posted Date
- 2019-02-22
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 30
- Registration Number
- NCT02885636
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Measurement of Respiratory Admittance for Pediatric Asthma Diagnosis
- Conditions
- Interventions
- First Posted Date
- 2016-08-24
- Last Posted Date
- 2016-08-24
- Lead Sponsor
- Central Hospital, Nancy, France
- Target Recruit Count
- 177
- Registration Number
- NCT02877537
- Locations
- 🇫🇷
CHU de Nancy - Hôpital BRABOIS Enfants - Explorations fonctionnelles pédiatriques, Vandœuvre-lès-Nancy, France
Phase I, Placebo-Controlled, Blinded Pilot Study of Ipratropium in Children Admitted to the ICU With Status Asthmaticus
- Conditions
- Interventions
- First Posted Date
- 2016-08-19
- Last Posted Date
- 2019-04-18
- Lead Sponsor
- University Hospitals Cleveland Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT02872597
- Locations
- 🇺🇸
Rainbow Babies and Children's Hospital (of Univ. Hospitals Case Med. Center), Cleveland, Ohio, United States
Evaluation of Aerosolized Drugs Deposition During Mechanical Ventilation
- Conditions
- Interventions
- First Posted Date
- 2016-06-29
- Last Posted Date
- 2017-02-01
- Lead Sponsor
- Chang Gung University
- Target Recruit Count
- 30
- Registration Number
- NCT02818270
- Locations
- 🇨🇳
Chiayi Chang Gung Memorial Hospital, Chiayi, Taiwan
Change in Oxygen Consumption Following Inhalation Beta Agonists in Healthy Adults
- First Posted Date
- 2016-06-16
- Last Posted Date
- 2020-10-28
- Lead Sponsor
- Children's Hospital Los Angeles
- Target Recruit Count
- 24
- Registration Number
- NCT02802111
Secondhand Smoke Respiratory Health Study
- Conditions
- Interventions
- First Posted Date
- 2016-06-13
- Last Posted Date
- 2024-04-23
- Lead Sponsor
- University of California, San Francisco
- Target Recruit Count
- 107
- Registration Number
- NCT02797275
- Locations
- 🇺🇸
VA Medical Center, San Francisco, California, United States
🇺🇸University of California San Francisco, San Francisco, California, United States
The Development of Novel Clinical Tests to Diagnose and Monitor Asthma in Preschool Children
- Conditions
- Interventions
- First Posted Date
- 2016-04-19
- Last Posted Date
- 2021-02-08
- Lead Sponsor
- The Hospital for Sick Children
- Target Recruit Count
- 121
- Registration Number
- NCT02743663
- Locations
- 🇨🇦
The Hospital for Sick Children, Toronto, Ontario, Canada
Drug Development Updates
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