Cetirizine

Generic Name
Cetirizine
Brand Names
Aller-tec, Aller-tec D, Quzyttir, Reactine, Wal Zyr 24 Hour Allergy, Wal Zyr D, Wal-zyr, Zerviate, Zyrtec, Zyrtec-D
Drug Type
Small Molecule
Chemical Formula
C21H25ClN2O3
CAS Number
83881-51-0
Unique Ingredient Identifier
YO7261ME24
Background

Cetirizine, also commonly known as Zyrtec, is an orally active second-generation histamine H1 antagonist proven effective in the treatment of various allergic symptoms, such as sneezing, coughing, nasal congestion, hives, and other symptoms , .
...

Indication

Seasonal Allergic Rhinitis: Indicated for the relief of symptoms associated with seasonal allergic rhinitis caused by allergens such as ragweed, grass and tree pollens in adults and children 2 years of age and above. Symptoms treated effectively include sneezing, rhinorrhea, nasal pruritus, ocular pruritus, tearing, and redness of the eyes .
...

Associated Conditions
Allergy to Tree Pollen, Chronic Idiopathic Urticaria, Flu caused by Influenza, Perennial Allergic Rhinitis (PAR), Respiratory Allergy, Seasonal Allergic Rhinitis
Associated Therapies
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Efficacy and Safety of Cetirizine Tablets Versus Ketotifen Dry Syrup in Children With Perennial Allergic Rhinitis

Phase 3
Completed
Conditions
First Posted Date
2008-03-20
Last Posted Date
2009-09-04
Lead Sponsor
UCB Pharma
Target Recruit Count
149
Registration Number
NCT00639587

A Study To Investigate If MRI Scanning Is Effective At Seeing What Hayfever Drugs Do In Nasal Passage.

First Posted Date
2007-08-17
Last Posted Date
2013-09-02
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
21
Registration Number
NCT00517946
Locations
🇬🇧

GSK Investigational Site, London, United Kingdom

Efficacy Study for the Symptomatic Treatment of Seasonal Allergic Rhinitis

First Posted Date
2007-07-20
Last Posted Date
2012-04-05
Lead Sponsor
Faes Farma, S.A.
Target Recruit Count
683
Registration Number
NCT00504933

Cetirizine Placebo Controlled Study For Perennial Allergic Rhinitis

Phase 3
Completed
Conditions
First Posted Date
2007-06-22
Last Posted Date
2017-08-29
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
239
Registration Number
NCT00490204
Locations
🇯🇵

GSK Investigational Site, Tokyo, Japan

Comparison of the Effect of Montelukast and Cetirizine on Allergic Inflammation in Children With Allergic Rhinitis

First Posted Date
2007-06-20
Last Posted Date
2013-02-07
Lead Sponsor
Medical University of Lodz
Target Recruit Count
116
Registration Number
NCT00488176
Locations
🇵🇱

Department of Pediatrics and Allergy, Medical University of Lodz Lodz, Poland, Lodz, Poland

A Randomized, Double-Blind, 4-way Crossover Study to Evaluate the Efficacy of Bilastine in the Vienna Challenge Chamber

First Posted Date
2007-01-09
Last Posted Date
2012-04-05
Lead Sponsor
Faes Farma, S.A.
Target Recruit Count
75
Registration Number
NCT00420082
Locations
🇦🇹

Allergy Center Vienna West, Vienna, Austria

Study to Assess the Effect of a Combination of Cetirizine With Pseudoephedrine Versus Cetirizine Alone on Symptoms in Patients With Allergic Rhinitis

Not Applicable
Completed
Conditions
First Posted Date
2006-06-08
Last Posted Date
2010-02-03
Lead Sponsor
Fraunhofer-Institute of Toxicology and Experimental Medicine
Target Recruit Count
51
Registration Number
NCT00334698
Locations
🇩🇪

Fraunhofer-Institute of Toxicology and Experimental Medicine, Hannover, Germany

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