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Meclizine

Generic Name
Meclizine
Brand Names
Antivert, Bonine, Diphen, Dramamine, Travel-ease
Drug Type
Small Molecule
Chemical Formula
C25H27ClN2
CAS Number
569-65-3
Unique Ingredient Identifier
3L5TQ84570

Overview

Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets.

Background

Meclizine is a histamine H1 antagonist with antiemetic and antivertigo properties. It is used in the symptomatic treatment of motion sickness and control of vertigo associated with vestibular system diseases. It also exhibits anticholinergic, central nervous system depressant, and local anesthetic effects. Commonly marketed under the brand name Antivert in the U.S., meclizine is available as oral tablets.

Indication

Indicated for the symptomatic treatment of nausea, vomiting, and dizziness associated with motion sickness, and management of vertigo due to various causes, including radiation sickness, Meniere’s syndrome, labyrinthitis and other vestibular disturbances.

Associated Conditions

  • Motion Sickness
  • Vertigo

Clinical Trials

FDA Approved Products

MECLIZINE HYDROCHLORIDE
Manufacturer:Aurobindo Pharma Limited
Route:ORAL
Strength:12.5 mg in 1 1
Approved: 2023/09/15
NDC:59651-807
Meclizine Hydrochloride
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:25 mg in 1 1
Approved: 2020/06/26
NDC:50090-5727
MECLIZINE HYDROCHLORIDE
Manufacturer:RPK Pharmaceuticals, Inc.
Route:ORAL
Strength:25 mg in 1 1
Approved: 2019/12/20
NDC:53002-3510
MECLIZINE HYDROCHLORIDE
Manufacturer:Northwind Pharmaceuticals, LLC
Route:ORAL
Strength:25 mg in 1 1
Approved: 2015/03/23
NDC:51655-134
Meclizine Hydrochloride
Manufacturer:Quality Care Products, LLC
Route:ORAL
Strength:12.5 mg in 1 1
Approved: 2023/08/02
NDC:83008-022

Singapore Approved Products

No Singapore products found for this drug

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