Sulodexide

Generic Name
Sulodexide
Brand Names
-
Drug Type
Biotech
Chemical Formula
-
CAS Number
57821-29-1
Unique Ingredient Identifier
75HGV0062C
Background

Sulodexide is a mixture of glycosaminoglycans (GAGs) composed of dermatan sulfate (DS) and fast moving heparin (FMH).

Indication

Sulodexide has been used clinically for the prophylaxis and treatment of vascular diseases with increased risk of thrombosis, including intermittent claudication, peripheral arterial occlusive disease and post-myocardial infarc-tion. Also investigated in the treatment of diabetic kidney disease and diabetic neuropathy. New anti-inflammatory properties have a...

Associated Conditions
Venous Leg Ulcer (VLU), Chronic Venous Ulcers
Associated Therapies
-

The Efficacy and Safety Study of Sulodexide in Filipino Diabetic Patients With Chronic Kidney Disease

First Posted Date
2009-10-23
Last Posted Date
2009-10-30
Lead Sponsor
Corbridge Group Philippines, Inc.
Target Recruit Count
1508
Registration Number
NCT01000545
Locations
🇵🇭

Mary Mediatrix Medical Center, Lipa City, Batangas, Philippines

🇵🇭

Rizal Private Clinics, Metro Manila, Rizal, Philippines

🇵🇭

Holy Child Hospital, Dumaguete City, Philippines

and more 4 locations

Sulodexide Treatment in Patients With Dense Deposit Disease

Phase 1
Withdrawn
Conditions
Interventions
First Posted Date
2007-12-31
Last Posted Date
2015-06-11
Lead Sponsor
University of Iowa
Registration Number
NCT00583427
Locations
🇺🇸

Richard Smith, MD, Iowa City, Iowa, United States

Open Label Tolerability and Safety Study of KRX-101 in Australia, New Zealand, and Hong Kong

Phase 3
Terminated
Conditions
Interventions
First Posted Date
2007-04-18
Last Posted Date
2017-03-03
Lead Sponsor
Keryx Biopharmaceuticals
Target Recruit Count
200
Registration Number
NCT00462202
Locations
🇦🇺

Monash Medical Center, Melbourne, Victoria, Australia

Effect of Sulodexide in Overt Diabetic Nephropathy

Phase 4
Terminated
Conditions
Interventions
First Posted Date
2005-08-15
Last Posted Date
2021-03-19
Lead Sponsor
Keryx Biopharmaceuticals
Target Recruit Count
968
Registration Number
NCT00130312
Locations
🇺🇸

The Collaborative Study Group, Clinical Coordinating Center for U.S. and Canadian clinics, Rush University Medical Center, Chicago, Illinois, United States

🇳🇱

The Collaborative Study Group, Clinical Coordinating Center for European Clinics, University of Groningen, Groningen, Netherlands

🇦🇺

The Collaborative Study Group, Clinical Coordinating Center for the Pacific Region, Monash Medical Center, Melbourne, Victoria, Australia

Effect of Sulodexide in Early Diabetic Nephropathy

Phase 3
Completed
Conditions
Interventions
First Posted Date
2005-08-15
Last Posted Date
2018-03-23
Lead Sponsor
Keryx Biopharmaceuticals
Target Recruit Count
1056
Registration Number
NCT00130208
Locations
🇳🇱

The Collaborative Study Group, Clinical Coordinating Center for European Clinics, University of Groningen, Groningen, Netherlands

🇺🇸

The Collaborative Study Group, Clinical Coordinating Center for U.S. and Canadian Clinics, Rush University Medical Center, Chicago, Illinois, United States

🇦🇺

The Collaborative Study Group, Clinical Coordinating Center for the Pacific Region, Monash Medical Center, Melbourne, Victoria, Australia

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