Clopidogrel
- Generic Name
- Clopidogrel
- Brand Names
- Duoplavin, Plavix, Zyllt, Clopidogrel BGR (previously Zylagren), Clopidogrel TAD, Clopidogrel ratiopharm, Clopidogrel Zentiva (previously Clopidogrel Winthrop), Clopidogrel Krka, Clopidogrel Krka d.d. (previously Zopya), Clopidogrel Teva (hydrogen sulphate), Clopidogrel HCS, Iscover, Grepid, Clopidogrel Taw Pharma (previously Clopidogrel Mylan), Clopidogrel Viatris (previously Clopidogrel Taw Pharma)
- Drug Type
- Small Molecule
- Chemical Formula
- C16H16ClNO2S
- CAS Number
- 113665-84-2
- Unique Ingredient Identifier
- A74586SNO7
- Background
Clopidogrel is a prodrug of a platelet inhibitor used to reduce the risk of myocardial infarction and stroke. Clopidogrel is indicated to reduce the risk of myocardial infarction for patients with non-ST elevated acute coronary syndrome (ACS), patients with ST-elevated myocardial infarction, and in recent MI, stroke, or established peripheral arterial diseas...
- Indication
1.用于新近心肌梗死、新近脑卒中或确诊的周围动脉病变患者，可减少新的缺血性脑卒中、心肌梗死和死亡等心脑血管事件的符合终点；
2.用于急性冠状动脉综合征（不稳定心绞痛和非ST段抬高心肌梗死）患者；
3.用于冠状动脉支架置入术后预防支架内血栓形成（与阿司匹林联用）。
- Associated Conditions
- Acute Coronary Syndrome (ACS), Acute Myocardial Infarction (AMI), Cardiovascular Events, Atherothrombotic events
- Associated Therapies
- -
Aspirin Combined With Clopidogrel Versus Intravenous Alteplase for Acute Minor Stroke
- Conditions
- Interventions
- First Posted Date
- 2023-06-18
- Last Posted Date
- 2023-06-18
- Target Recruit Count
- 472
- Registration Number
- NCT05910125
- Locations
- 🇨🇳
Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, Guangdong, China
Ticagrelor vs. Clopidogrel in Post PCI Patients
- Conditions
- Interventions
- First Posted Date
- 2023-05-15
- Last Posted Date
- 2023-05-16
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 476
- Registration Number
- NCT05858918
- Locations
- 🇮🇷
Professor Kojuri Cardiology Clinic, Shiraz, Iran, Islamic Republic of
Pharmacodynamic Outcomes in CCS Patients Treated With an Individualized Treatment Strategy
- Conditions
- Interventions
- First Posted Date
- 2023-03-17
- Last Posted Date
- 2024-01-26
- Lead Sponsor
- St. Antonius Hospital
- Target Recruit Count
- 88
- Registration Number
- NCT05773989
- Locations
- 🇳🇱
St. Antonius Hospital, Nieuwegein, Utrecht, Netherlands
Anticoagulation Using Rivaroxaban on Top of Aspirin in Intracranial Atherosclerotic Stenosis
- Conditions
- Interventions
- First Posted Date
- 2023-01-26
- Last Posted Date
- 2023-12-21
- Target Recruit Count
- 1180
- Registration Number
- NCT05700266
Body Weight Adjusted Clopidogrel Treatment in Patients With CORonary Artery Disease
- First Posted Date
- 2022-12-20
- Last Posted Date
- 2023-06-02
- Lead Sponsor
- St. Antonius Hospital
- Target Recruit Count
- 80
- Registration Number
- NCT05657041
- Locations
- 🇳🇱
StAntoniusH, Nieuwegein, Utrecht, Netherlands
🇳🇱St. Antonius Hospital, Nieuwegein, Netherlands
Multicentric Study on Clopidogrel Resistance in DAPT for CAS (MULTI-RESCLOSA)
- Conditions
- Interventions
- First Posted Date
- 2022-10-04
- Last Posted Date
- 2023-12-28
- Lead Sponsor
- IRCCS Policlinico S. Donato
- Target Recruit Count
- 1140
- Registration Number
- NCT05566301
- Locations
- 🇮🇹
IRCCS Policlinico San Donato, San Donato Milanese, Milan, Italy
Impact of CYP2C19 Genotype-guided Clopidogrel and Ticagrelor Treatment on Platelet Function Test and Metabolomics Profile
- Conditions
- Interventions
- First Posted Date
- 2022-08-26
- Last Posted Date
- 2022-09-01
- Lead Sponsor
- Universiti Sains Malaysia
- Target Recruit Count
- 80
- Registration Number
- NCT05516784
- Locations
- 🇲🇾
Department of Cardiology, Penang General Hospital, George Town, Penang, Malaysia
A REAl-life Study on Short-term DAPT in Patients With Ischemic Stroke or TIA
- First Posted Date
- 2022-07-27
- Last Posted Date
- 2024-12-05
- Lead Sponsor
- University of L'Aquila
- Target Recruit Count
- 2239
- Registration Number
- NCT05476081
- Locations
- 🇮🇹
Neurology e Stroke Unit Departement, SS Filippo e Nicola Hospital, Avezzano, Abruzzo, Italy
🇮🇹Department of Neurology and Stroke Unit, Ente Ecclesiastico ospedale Generale Regionale Miulli, Acquaviva Delle Fonti, Italy
🇮🇹Department of Neurology, Murgia Hospital Fabio Perinei SS 96, Altamura, Italy
Clopidogrel Monotherapy in Patients With High Bleeding Risk
- Conditions
- Interventions
- First Posted Date
- 2022-02-03
- Last Posted Date
- 2024-02-21
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 98
- Registration Number
- NCT05223335
- Locations
- 🇺🇸
Mayo Clinic in Rochester, Rochester, Minnesota, United States
Paclitaxel-Coated Balloon Versus Zotarolimus-Eluting Stent for Treatment of De Novo Coronary Artery Lesions
- Conditions
- Interventions
- First Posted Date
- 2022-01-26
- Last Posted Date
- 2024-01-24
- Lead Sponsor
- Xijing Hospital
- Target Recruit Count
- 370
- Registration Number
- NCT05209412
- Locations
- 🇨🇳
Ling Tao, Xi'an, Shannxi, China
Drug Development Updates
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