MedPath

Sargramostim

Generic Name
Sargramostim
Brand Names
Leukine
Drug Type
Biotech
CAS Number
123774-72-1
Unique Ingredient Identifier
5TAA004E22

Overview

Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.

Background

Sargramostim is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein.

Indication

For the treatment of cancer and bone marrow transplant

Associated Conditions

  • Acute Lymphoblastic Leukemia (ALL)
  • Hematopoietic Subsyndrome of Acute Radiation Syndrome
  • Hodgkin's Lymphoma
  • Neutropenia
  • Non-Hodgkin's Lymphoma (NHL)
  • Severe Infection

FDA Approved Products

Leukine
Manufacturer:Partner Therapeutics, Inc.
Route:SUBCUTANEOUS, INTRAVENOUS
Strength:250 ug in 1 mL
Approved: 2023/08/31
NDC:71837-5843

Singapore Approved Products

No Singapore products found for this drug

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