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Vimseltinib

Generic Name
Vimseltinib
Drug Type
Small Molecule
Chemical Formula
C23H25N7O2
CAS Number
1628606-05-2
Unique Ingredient Identifier
PX9FTM69BF

A Study to Evaluate Vimseltinib in Adults With Active Chronic Graft-Versus-Host Disease (cGVHD)

Phase 2
Recruiting
Conditions
Chronic Graft-Versus-Host Disease (cGVHD)
Interventions
First Posted Date
2024-10-01
Last Posted Date
2025-05-21
Lead Sponsor
Deciphera Pharmaceuticals, LLC
Target Recruit Count
36
Registration Number
NCT06619561
Locations
๐Ÿ‡บ๐Ÿ‡ธ

City of Hope National Medical Center, Duarte, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

Ronald Regan UCLA Medical Center, Los Angeles, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

AdventHealth Orlando, Orlando, Florida, United States

and more 8 locations

Study of Vimseltinib for Tenosynovial Giant Cell Tumor

Phase 3
Active, not recruiting
Conditions
Tenosynovial Giant Cell Tumor, Diffuse
Tenosynovial Giant Cell Tumor
Pigmented Villonodular Synovitis
Tenosynovial Giant Cell Tumor, Localized
Giant Cell Tumor of Tendon Sheath
Interventions
Drug: Placebo
First Posted Date
2021-09-28
Last Posted Date
2025-02-24
Lead Sponsor
Deciphera Pharmaceuticals, LLC
Target Recruit Count
123
Registration Number
NCT05059262
Locations
๐Ÿ‡ช๐Ÿ‡ธ

Hospital Universitario Vall d'Hebron, Barcelona, Spain

๐Ÿ‡บ๐Ÿ‡ธ

Ohio State University, Columbus, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Colorado, Aurora, Colorado, United States

and more 32 locations

Study of DCC-3014 in Combination With Avelumab in Patients With Advanced or Metastatic Sarcomas

Phase 1
Active, not recruiting
Conditions
Sarcoma
Advanced Sarcoma
High Grade Sarcoma
Leiomyosarcoma
Undifferentiated Pleomorphic Sarcoma
Myxofibrosarcoma
Dedifferentiated Liposarcoma
Interventions
First Posted Date
2020-01-27
Last Posted Date
2025-05-16
Lead Sponsor
Memorial Sloan Kettering Cancer Center
Target Recruit Count
32
Registration Number
NCT04242238
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Memorial Sloan Kettering Cancer Center, New York, New York, United States

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Phase 1
Active, not recruiting
Conditions
Giant Cell Tumor of Tendon Sheath
Tenosynovial Giant Cell Tumor, Diffuse
Advanced Malignant Neoplasm
Tenosynovial Giant Cell Tumor
Pigmented Villonodular Synovitis
Interventions
First Posted Date
2017-03-03
Last Posted Date
2024-11-20
Lead Sponsor
Deciphera Pharmaceuticals, LLC
Target Recruit Count
120
Registration Number
NCT03069469
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Stanford Cancer Institute, Palo Alto, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

MSKCC, New York, New York, United States

๐Ÿ‡ฆ๐Ÿ‡บ

Peter MacCallum Cancer Centre, Melbourne, Australia

and more 21 locations
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