Misoprostol
- Generic Name
- Misoprostol
- Brand Names
- Arthrotec, Cytotec, Mifegymiso
- Drug Type
- Small Molecule
- Chemical Formula
- C22H38O5
- CAS Number
- 59122-46-2
- Unique Ingredient Identifier
- 0E43V0BB57
- Background
Misoprostol is a prostaglandin analog used to reduce the risk of NSAID related ulcers, manage miscarriages, prevent post partum hemorrhage, and also for first trimester abortions. The stimulation of prostaglandin receptors in the stomach reduces gastric acid secretion, while stimulating these receptors in the uterus and cervix can increase the strength and f...
- Indication
Misoprostol is indicated as a tablet to reduce the risk of NSAID induced gastric ulcers but not duodenal ulcers in high risk patients. Misoprostol is also formulated in combination with diclofenac to treat symptoms of osteoarthritis or rheumatoid arthritis in patients with a high risk of developing gastric ulcers. Misoprostol is used off label for the manage...
- Associated Conditions
- Gastric Ulcer, Incomplete Abortion, Missed Abortion, Postpartum Haemorrhage (PPH)
- Associated Therapies
- Induction of cervix ripening therapy, Medically induced abortion
Pilot Study of an Ambulatory Medical Abortion Service at 13-18 Weeks of Gestation in Colombia
- Conditions
- Interventions
- First Posted Date
- 2019-08-21
- Last Posted Date
- 2021-07-23
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 16
- Registration Number
- NCT04063904
- Locations
- 🇨🇴
Fundacion Orientame, Bogotá, Colombia
Vaginal Dinoprostone Versus Vaginal Misoprostol Prior to Diagnostic Office Hysteroscopy in Postmenopausal Patients
- Conditions
- Interventions
- First Posted Date
- 2019-08-02
- Last Posted Date
- 2020-09-01
- Lead Sponsor
- Cairo University
- Target Recruit Count
- 150
- Registration Number
- NCT04044079
- Locations
- 🇪🇬
Ahmed Samy, Giza, Egypt
Pitocin or Oral Misoprostol for PROM IOL
- First Posted Date
- 2019-07-23
- Last Posted Date
- 2024-04-30
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 108
- Registration Number
- NCT04028765
- Locations
- 🇺🇸
Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
Labor Protocol Study
- Conditions
- Interventions
- First Posted Date
- 2019-07-02
- Last Posted Date
- 2022-10-04
- Lead Sponsor
- Montefiore Medical Center
- Target Recruit Count
- 66
- Registration Number
- NCT04004845
- Locations
- 🇺🇸
Montefiore Medical Center Weiler Division / Albert Einstein College of Medicine, Bronx, New York, United States
Buccal Versus Vaginal Misoprostol In Combination With Foley Bulb
- First Posted Date
- 2019-06-05
- Last Posted Date
- 2021-02-26
- Lead Sponsor
- Christiana Care Health Services
- Target Recruit Count
- 216
- Registration Number
- NCT03976037
- Locations
- 🇺🇸
Christiana Care Health Systems, Newark, Delaware, United States
Assessing Medical Menstrual Regulation in the United States
- First Posted Date
- 2019-06-03
- Last Posted Date
- 2021-03-24
- Lead Sponsor
- Gynuity Health Projects
- Target Recruit Count
- 284
- Registration Number
- NCT03972358
- Locations
- 🇺🇸
Carafem Health Center, Chevy Chase, Maryland, United States
Role of Vaginal Misoprostol Prior to IUCD Insertion in Women Who Delivered Only by Elective Caesarean Section.
- First Posted Date
- 2019-05-07
- Last Posted Date
- 2019-05-07
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 210
- Registration Number
- NCT03939663
- Locations
- 🇪🇬
Enas Mahmoud, Cairo, Egypt
Vasopressin Injection Versus Misoprostol During Hysteroscopic Myomectomy In Reducing Blood Loss And Operation Time.
- Conditions
- Interventions
- First Posted Date
- 2019-04-29
- Last Posted Date
- 2019-04-29
- Lead Sponsor
- Zagazig University
- Target Recruit Count
- 40
- Registration Number
- NCT03930069
Labor Induction With a Combined Method (Pharmacologic and Mechanical): Randomized Controlled Trial
- Conditions
- Interventions
- First Posted Date
- 2019-04-26
- Last Posted Date
- 2023-01-23
- Lead Sponsor
- Centro Hospitalar De São João, E.P.E.
- Target Recruit Count
- 140
- Registration Number
- NCT03928600
- Locations
- 🇵🇹
Centro Hospitalar São João, Porto, Portugal
Oral Misoprostol Solution in Labor Induction
- First Posted Date
- 2019-04-25
- Last Posted Date
- 2019-04-25
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 150
- Registration Number
- NCT03927807
- Locations
- 🇪🇬
Ain Shams University, Cairo, Cairo Governorate, Egypt
Drug Development Updates
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