Aripiprazole

Generic Name
Aripiprazole
Brand Names
Abilify, Aripiprazole Mylan Pharma (previously Aripiprazole Pharmathen), Abilify Maintena, Aripiprazole Accord, Aripiprazole Sandoz, Aripiprazole Zentiva
Drug Type
Small Molecule
Chemical Formula
C23H27Cl2N3O2
CAS Number
129722-12-9
Unique Ingredient Identifier
82VFR53I78
Background

Aripiprazole is an atypical antipsychotic orally indicated for the treatment of schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's. It is also indicated as an injection for agitation associated with schizophrenia or bipolar mania. Aripiprazole exerts its effects through agonism of dopaminergic and 5-HT1A ...

Indication

Aripiprazole is indicated for the treatment of acute manic and mixed episodes associated with bipolar I disorder, irritability associated with autism spectrum disorder, schizophrenia, and Tourette's disorder. It is also used as an adjunctive treatment of major depressive disorder.[L45859 An injectable formulation of aripiprazole is indicated for agitation as...

Associated Conditions
Agitation, Bipolar 1 Disorder, Irritability, Major Depressive Disorder (MDD), Mixed manic depressive episode, Psychosis, Psychotic Depression, Schizophrenia, Tourette's Disorder (TD), Acute Manic episode
Associated Therapies
Monotherapy

Study of Three Doses of Aripiprazole in Patients With Acute Schizophrenia

Phase 4
Completed
Conditions
Interventions
First Posted Date
2004-03-30
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
370
Registration Number
NCT00080327
Locations
🇺🇸

Bristol-Meyers Squibb Call Center, Wallingford, Connecticut, United States

Study of Aripiprazole in Patients With Bipolar I Disorder With a Major Depression Episode

Phase 3
Completed
Conditions
Interventions
First Posted Date
2004-03-30
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
400
Registration Number
NCT00080314
Locations
🇺🇸

Local Institution, Bellevue, Washington, United States

🇺🇸

Local Insstitution, Honolulu, Hawaii, United States

Study of Aripiprazole in the Treatment of Patients With Acute Symptoms of Bipolar Disorder

Phase 3
Completed
Conditions
First Posted Date
2002-10-01
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Registration Number
NCT00046384
Locations
🇦🇷

Local Institution, Mendoza, Argentina

Switching Medication to Treat Schizophrenia

First Posted Date
2002-09-05
Last Posted Date
2016-04-28
Lead Sponsor
Icahn School of Medicine at Mount Sinai
Target Recruit Count
219
Registration Number
NCT00044655

Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type

Phase 3
Completed
Conditions
First Posted Date
2002-07-15
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Registration Number
NCT00041678
Locations
🇺🇸

Local Institution, Milwaukee, Wisconsin, United States

Study of Aripiprazole in Patients With a History of Bipolar Disorder

Phase 3
Completed
Conditions
First Posted Date
2002-05-10
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Registration Number
NCT00036348
Locations
🇺🇸

Local Institution, San Antonio, Texas, United States

Broad Effectiveness: Study With Aripiprazole

Phase 3
Completed
Conditions
First Posted Date
2002-05-10
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Target Recruit Count
444
Registration Number
NCT00036361
Locations
🇺🇸

Local Institution, Wallingford, Connecticut, United States

Study of Aripiprazole in the Treatment of Patients With Acute Symptoms in Bipolar Disorder

Phase 3
Completed
Conditions
First Posted Date
2002-05-09
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Registration Number
NCT00036101
Locations
🇺🇸

Local Institution, Bellevue, Washington, United States

Study of Aripiprazole in the Treatment of Patients With Psychosis Associated With Dementia of the Alzheimer's Type

Phase 3
Completed
Conditions
First Posted Date
2002-05-09
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Registration Number
NCT00036114
Locations
🇺🇸

Local Institution, Seattle, Washington, United States

Study of Alternate Formulation of Aripiprazole in Agitated Patients With Schizophrenic Disorders

Phase 2
Completed
Conditions
First Posted Date
2002-05-09
Last Posted Date
2013-11-11
Lead Sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Registration Number
NCT00036127
Locations
🇺🇸

Local Instituton, Hoffman Estates, Illinois, United States

🇺🇸

Local Institution, Milwaukee, Wisconsin, United States

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