Olmesartan

Generic Name
Olmesartan
Brand Names
Azor, Benicar, Benicar Hct, Olmetec, Olmetec Plus, Tribenzor
Drug Type
Small Molecule
Chemical Formula
C24H26N6O3
CAS Number
144689-24-7
Unique Ingredient Identifier
8W1IQP3U10
Background

Olmesartan belongs to the angiotensin II receptor blocker (ARB) family of drugs, which also includes telmisartan, candesartan, losartan, valsartan, and irbesartan. ARBs selectively bind to angiotensin receptor 1 (AT1) and prevent the protein angiotensin II from binding and exerting its hypertensive effects, which include vasoconstriction, stimulation and syn...

Indication

Olmesartan is indicated for the treatment of hypertension either alone or in combination with other antihypertensive agents.
...

Associated Conditions
Diabetic Nephropathy, Hypertension
Associated Therapies
-

Treatment of High Blood Pressure Using Olmesartan With Hydrochlorothiazide Compared to an ACE Inhibitor With a Calcium Channel Blocker

Phase 4
Completed
Conditions
First Posted Date
2005-09-16
Last Posted Date
2012-01-18
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
152
Registration Number
NCT00185120
Locations
🇺🇸

National Research Institute, Los Angeles, California, United States

🇺🇸

Apex Research Institute, Santa Ana, California, United States

🇺🇸

Orange County Research Center, Tustin, California, United States

and more 16 locations

Olmesartan Medoxomil in Hypertension and Renal Impairment

First Posted Date
2005-09-09
Last Posted Date
2010-10-14
Lead Sponsor
Sankyo Pharma Gmbh
Target Recruit Count
393
Registration Number
NCT00151827

Assessment of Efficacy and Safety of Olmesartan Medoxomil in Children and Adolescent Patients With High Blood Pressure

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-09-09
Last Posted Date
2016-06-30
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
362
Registration Number
NCT00151775

Olmesartan Pediatric Pharmacokinetic (PK) Study

Phase 1
Completed
Conditions
Interventions
First Posted Date
2005-09-09
Last Posted Date
2010-04-15
Lead Sponsor
Daiichi Sankyo
Target Recruit Count
24
Registration Number
NCT00151814

ORIENT: Olmesartan Reducing Incidence of End Stage Renal Disease in Diabetic Nephropathy Trial

First Posted Date
2005-09-01
Last Posted Date
2011-05-10
Lead Sponsor
Daiichi Sankyo Co., Ltd.
Target Recruit Count
577
Registration Number
NCT00141453

OlmeSartan and Calcium Antagonists Randomized (OSCAR) Study

First Posted Date
2005-08-24
Last Posted Date
2010-10-05
Lead Sponsor
OSCAR Study
Target Recruit Count
1000
Registration Number
NCT00134160
Locations
🇯🇵

Department of Cardiovascular Medicine Graduate School of Medical Science Kumamoto University, 1-1-1 Honjyo, Kumamoto-City, Kumamoto, Japan

🇯🇵

OSCAR-Study Data Center, ShinjukuParkTower30FN, 3-7-1 Nishi-Shinjuku, Shinjuku-ku, Tokyo, Japan

Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance

First Posted Date
2005-07-22
Last Posted Date
2013-12-05
Lead Sponsor
Emory University
Target Recruit Count
84
Registration Number
NCT00122447
Locations
🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

🇺🇸

Grady Health System, Atlanta, Georgia, United States

Trial to Investigate the Efficacy of Olmesartan in Paroxysmal Atrial Fibrillation

Phase 3
Completed
Conditions
Interventions
First Posted Date
2004-12-06
Last Posted Date
2012-09-11
Lead Sponsor
Atrial Fibrillation Network
Target Recruit Count
422
Registration Number
NCT00098137
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