Glucagon

Generic Name
Glucagon
Brand Names
Baqsimi, Glucagen, Gvoke, Ogluo
Drug Type
Biotech
Chemical Formula
-
CAS Number
16941-32-5
Unique Ingredient Identifier
76LA80IG2G
Background

Glucagon is a 29 amino acid hormone used as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia. Glucagon raises blood sugar through activation of hepatic glucagon receptors, stimulating glycogenolysis and the release of glucose.
...

Indication

Glucagon is indicated as a diagnostic aid in radiologic exams to temporarily inhibit the movement of the gastrointestinal tract and to treat severe hypoglycemia.

Associated Conditions
Severe Hypoglycemia
Associated Therapies
-

Trial to Compare the Relative Pharmacodynamic Properties of Different Glucagon Dosages

Phase 1
Completed
Conditions
Interventions
First Posted Date
2013-08-05
Last Posted Date
2014-02-05
Lead Sponsor
Profil Institut für Stoffwechselforschung GmbH
Target Recruit Count
6
Registration Number
NCT01916265
Locations
🇩🇪

Profil Institut für Stoffwechselforschung GmbH, Neuss, NRW, Germany

Efficacy of Small Subcutaneous Glucagon Dose to Treat Hypoglycemia in Adults With Type 1 Diabetes

First Posted Date
2013-04-10
Last Posted Date
2013-12-04
Lead Sponsor
Institut de Recherches Cliniques de Montreal
Registration Number
NCT01828125
Locations
🇨🇦

Institut de recherches cliniques de Montréal, Montreal, Quebec, Canada

Study of Glucagon, Ghrelin and Growth Hormone as Counterregulatory Hormones

First Posted Date
2013-02-20
Last Posted Date
2013-02-20
Lead Sponsor
University of Virginia
Target Recruit Count
6
Registration Number
NCT01795235
Locations
🇺🇸

University of Virginia, Charlottesville, Virginia, United States

Effect of Glucagon on Uterine Contractility at the Time of Embryo Transfer in in Vitro Fertilization

Phase 4
Withdrawn
Conditions
Interventions
First Posted Date
2012-08-28
Last Posted Date
2015-07-28
Lead Sponsor
Clinique Ovo
Registration Number
NCT01674283
Locations
🇨🇦

Clinique Ovo, Montréal, Quebec, Canada

Study of LY2409021 in Participants With Type 1 Diabetes

First Posted Date
2012-07-16
Last Posted Date
2018-10-29
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
20
Registration Number
NCT01640834
Locations
🇩🇪

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Neuss, Germany

Physiologic Response to Glucagon at Varying Insulin Levels

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2011-12-01
Last Posted Date
2016-03-29
Lead Sponsor
Legacy Health System
Target Recruit Count
11
Registration Number
NCT01483651
Locations
🇺🇸

Legacy Health System, Portland, Oregon, United States

Effect of LY2189265 on Insulin Secretion in Response to Intravenous Glucose

First Posted Date
2011-02-21
Last Posted Date
2014-10-07
Lead Sponsor
Eli Lilly and Company
Target Recruit Count
32
Registration Number
NCT01300260
Locations
🇩🇪

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician., Neuss, Germany

Acute Regulation of Intestinal and Hepatic Lipoprotein Production by Glucagon

Phase 4
Completed
Conditions
Interventions
First Posted Date
2010-07-01
Last Posted Date
2015-12-02
Lead Sponsor
University Health Network, Toronto
Target Recruit Count
9
Registration Number
NCT01155206
Locations
🇨🇦

University Health Network, Toronto General Hospital, Toronto,, Ontario, Canada

A Phase 1 Study to Evaluate the Safety and Tolerability of GSK1362885 in Healthy Normal Subjects

First Posted Date
2009-01-16
Last Posted Date
2017-07-07
Lead Sponsor
GlaxoSmithKline
Target Recruit Count
42
Registration Number
NCT00823940
Locations
🇺🇸

GSK Investigational Site, Minneapolis, Minnesota, United States

To Evaluate the Response to Glucagon During Hypoglycemia

Phase 1
Completed
Conditions
Interventions
First Posted Date
2009-01-06
Last Posted Date
2009-05-07
Lead Sponsor
AstraZeneca
Target Recruit Count
8
Registration Number
NCT00817271
Locations
🇺🇸

Research Site, Chula Vista, California, United States

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