Betamethasone

Generic Name: Betamethasone

Brand Names: Betaderm, Betaloan Suik, Beteflam, Celestoderm, Celestone Soluspan, Dermacinrx Therazole Pak, Diprolene, Diprosalic, Diprosone, Dovobet, Enstilar, Fucibet, Lotriderm, Lotrisone, Luxiq, Marbeta, Rivasone, Rolene, Rosone, Sernivo, Taclonex, Valisone-G, Wynzora

Drug Type: Small Molecule

Chemical Formula: C_₂₂H_₂₉FO_₅

CAS Number: 378-44-9

Unique Ingredient Identifier: 9842X06Q6M

Background: Betamethasone is a long-acting corticosteroid with immunosuppressive and antiinflammatory properties. It can be used topically to manage inflammatory skin conditions such as eczema, and parenterally to manage several disease states including autoimmune disorders. Betamethasone has potent glucocorticoid activity and negligible mineralocorticoid activity.

Indication: As a member of the corticosteroid family, betamethasone is indicated for the treatment of several inflammatory conditions. As topical monotherapy, betamethasone is indicated to relieve pruritic and inflammatory symptoms of corticosteroid-responsive-dermatoses. Betamethasone can be used topically in combination with a vitamin D analog such as calcipotriene to...

Associated Conditions: Acute Gouty Arthritis, Adrenocortical Insufficiency, Alopecia Areata (AA), Ankylosing Spondylitis (AS), Atopic Dermatitis, Berylliosis, Blepharitis allergic, Blepharoconjunctivitis, Bullous dermatitis herpetiformis, Bursitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Conjunctivitis, Dermatomyositis (DM), Dermatosis, Discoid Lupus Erythematosus (DLE), Edema of the cerebrum, Epicondylitis, Episcleritis, External ear inflammation, Eye allergy, Hypercalcemia of Malignancy, Inflammatory Reaction of the ear, Iridocyclitis, Iritis, Itching caused by Allergies, Keloids Scars, Keratitis, Keratitis interstitial, Keratoconjunctivitis, Leukemias, Lichen Planus (LP), Lichen simplex chronicus, Lupus Erythematosus, Lymphoma, Multiple sclerosis exacerbation, Mycosis Fungoides (MF), Necrobiosis lipoidica diabeticorum, Nephrotic Syndrome, Ocular Inflammation, Ocular injuries, Ophthalmia, Sympathetic, Pemphigus, Plaque psoriasis of the body, Plaque psoriasis of the scalp, Polymyositis, Post Surgical Ocular Inflammation, Pruritus, Psoriasis, Psoriasis Vulgaris (Plaque Psoriasis), Psoriatic Arthritis, Psoriatic plaque, Pulmonary Tuberculosis (TB), Pure Red Cell Aplasia, Regional Enteritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Scleritis, Secondary thrombocytopenia, Severe Asthma, Severe Atopic Dermatitis, Skin Infections, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Temporal Arteritis, Trichinosis, Tuberculous Meningitis, Ulcerative Colitis, Uveitis, Verrucous Lichen Planus (LP), Acquired immune hemolytic anemia, Acute nonspecific tenosynovitis, Acute rheumatic carditis, Bacterial blepharitis, Corticosteroid-responsive dermatoses, Eczematous rash, Exfoliative erythroderma, Granuloma annulare lesions, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Ocular bacterial infections, Severe Allergic rhinitis, Severe Contact dermatitis, Severe Serum sickness, Severe Transfusion Reactions, Severe drug hypersensitivity reactions, Superficial ocular infections, Symptomatic Sarcoidosis, Synovitis of osteoarthritis

Associated Therapies: -

Clinical Trials

Comparison of Effect of Postoperative Cyclosporine A 2% Ophthalmic Emulsion and Betamethasone Eye Drop on Surgical Success of Trabeculectomy Procedure

Phase 2

Completed

Conditions: Glaucoma, Open Angle

Interventions: Drug: Cyclosporine
Drug: Betamethasone

First Posted Date: 2014-04-15

Last Posted Date: 2015-04-21

Lead Sponsor: Mashhad University of Medical Sciences

Target Recruit Count: 40

Registration Number: NCT02114073

Locations: 🇮🇷
Khatam Eye Hospital, Mashhad, Khorasan Razavi, Iran, Islamic Republic of

Navigator vs Standard Needle Injection for Hip

Phase 2

Completed

Conditions: Hip Pain Etiology Unknown

Interventions: Drug: Celestone
Drug: Lidocaine

First Posted Date: 2014-02-20

Last Posted Date: 2016-01-28

Lead Sponsor: Cartiva, Inc.

Target Recruit Count: 40

Registration Number: NCT02066844

Locations: 🇺🇸
University of Rochester, Rochester, New York, United States

Ultrasound-guided Injection for DeQuervain's

Phase 4

Terminated

Conditions: DeQuervain's Tenosynovitis

Interventions: Drug: Betamethasone
Device: Ultrasound

First Posted Date: 2014-01-16

Last Posted Date: 2022-12-28

Lead Sponsor: Medical College of Wisconsin

Target Recruit Count: 16

Registration Number: NCT02038634

Locations: 🇺🇸
Froedtert Hospital, Wauwatosa, Wisconsin, United States

Evaluation of Efficacy and Safety of Epidural Steroid Injection Using Dexamethasone or Betamethasone

Not Applicable

Completed

Conditions: Back Pain
Neck Pain

Interventions: Drug: Dexamethasone
Drug: Betamethasone

First Posted Date: 2013-06-25

Last Posted Date: 2016-03-30

Lead Sponsor: Seoul National University Bundang Hospital

Target Recruit Count: 600

Registration Number: NCT01885481

Locations: 🇰🇷
Seoul National University Bundang Hospital, Seongnam-si, Gyeonggi-do, Korea, Republic of

Effect of Antenatal Corticosteroids in Late Preterm

Phase 2

Conditions: Late Preterm

Interventions: Drug: betamethasone

First Posted Date: 2012-10-19

Last Posted Date: 2012-10-19

Lead Sponsor: Meir Medical Center

Target Recruit Count: 200

Registration Number: NCT01710384

SHP-141C in Plaque Type Psoriasis

Phase 1

Completed

Conditions: Plaque Type Psoriasis

Interventions: Drug: SHP-141C
Drug: Placebo to SHP-141C
Drug: Betamethasone Valerate
Drug: Calcipotriol

First Posted Date: 2012-07-20

Last Posted Date: 2014-07-11

Lead Sponsor: TetraLogic Pharmaceuticals

Target Recruit Count: 14

Registration Number: NCT01646567

Locations: 🇦🇺
Nucleus Network Limited, Melbourne, Victoria, Australia

LEO 90100 in the Treatment of Psoriasis Vulgaris

Phase 2

Completed

Conditions: Psoriasis Vulgaris

Interventions: Drug: LEO 90100
Drug: Betamethasone
Drug: Calcipotriol

First Posted Date: 2012-02-22

Last Posted Date: 2016-05-09

Lead Sponsor: LEO Pharma

Target Recruit Count: 303

Registration Number: NCT01536938

Locations: 🇺🇸
Dermatology Research Associates, Los Angeles, California, United States
🇺🇸
Altman Dermatology Associates, Arlington Heights, Illinois, United States
🇺🇸
Derm Research Center of New York, Stony Brook, New York, United States

and more 30 locations

Antenatal Late Preterm Steroids (ALPS): A Randomized Placebo-Controlled Trial

Phase 3

Completed

Conditions: Respiratory Distress Syndrome
Pregnancy
Preterm Birth
Pregnancy Outcomes

Interventions: Drug: Placebo
Drug: Betamethasone

First Posted Date: 2010-10-18

Last Posted Date: 2023-03-28

Lead Sponsor: The George Washington University Biostatistics Center

Target Recruit Count: 2831

Registration Number: NCT01222247

Locations: 🇺🇸
Ohio State University, Columbus, Ohio, United States
🇺🇸
University of Pittsburgh Magee Womens Hospital, Pittsburgh, Pennsylvania, United States
🇺🇸
Stanford University, Stanford, California, United States

and more 14 locations

Efficacy of Antenatal Steroids in Reducing Respiratory Morbidities in Late Preterm Infants

Phase 2

Conditions: Respiratory Distress Syndrome, Newborn
Transient Tachypnea of the Newborn

Interventions: Drug: Betamethasone
Other: Normal Saline

First Posted Date: 2010-09-22

Last Posted Date: 2011-06-23

Lead Sponsor: American University of Beirut Medical Center

Target Recruit Count: 700

Registration Number: NCT01206946

Locations: 🇱🇧
American University of Beirut Medical Center, Beirut, Lebanon
🇱🇧
Bahman Hospital, Beirut, Lebanon
🇱🇧
Rafik Hariri University Hospital, Beirut, Lebanon

and more 2 locations

Efficacy of Micro-Pulse Steroid Therapy as Induction Therapy in Patients With Polymyalgia Rheumatica

Not Applicable

Conditions: Polymyalgia Rheumatica

Interventions: Drug: Betamethasone
Drug: isotonic sodium chloride solution (placebo)

First Posted Date: 2009-09-23

Last Posted Date: 2010-07-20

Lead Sponsor: Bnai Zion Medical Center

Target Recruit Count: 20

Registration Number: NCT00982332

Locations: 🇮🇱
Bnai Zion Medical Center, Haifa, Israel

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

Home Terms & Conditions Privacy Policy