MedPath

NP-137

Generic Name
NP-137

Study of Perioperative NP137 and FOLFIRINOX in Resectable Pancreatic Cancer

Phase 1
Not yet recruiting
Conditions
Pancreatic Cancer
Interventions
First Posted Date
2024-01-12
Last Posted Date
2025-03-10
Lead Sponsor
Aram Hezel
Target Recruit Count
25
Registration Number
NCT06203821
Locations
🇺🇸

University of Rochester, Rochester, New York, United States

Acute Myeloid Leukemia Treated With With NETrin Abs in Combination With [AZACITIDINE + VENETOCLAX]

Phase 1
Terminated
Conditions
Acute Myeloid Leukemia Refractory
Interventions
First Posted Date
2023-11-29
Last Posted Date
2025-02-20
Lead Sponsor
Centre Leon Berard
Target Recruit Count
1
Registration Number
NCT06150040
Locations
🇫🇷

Centre Léon Bérard, Lyon, France

NP137 Clinical and Biological Activities Assessment in Patients with Advanced/Metastatic Solid Tumors Treated by Standard Anti PD-1/PD-L1 Immunotherapies

Phase 2
Recruiting
Conditions
Advanced Solid Tumors
Metastatic Solid Tumors
Interventions
Drug: anti-PD-1/PD-L1
First Posted Date
2022-11-04
Last Posted Date
2025-02-14
Lead Sponsor
Centre Leon Berard
Target Recruit Count
87
Registration Number
NCT05605496
Locations
🇫🇷

Centre Léon Bérard, Lyon, France

🇫🇷

Centre Antoine Lacassagne, Nice, France

🇫🇷

Institut Curie, Paris, France

and more 2 locations

Study Investigating the Association of NP137 With Atezolizumab-Bevacizumab Combination in First Line in Unresectable HCC

Phase 1
Recruiting
Conditions
Hepatocellular Carcinoma
Interventions
First Posted Date
2022-09-21
Last Posted Date
2024-03-08
Lead Sponsor
University Hospital, Grenoble
Target Recruit Count
52
Registration Number
NCT05546879
Locations
🇫🇷

CHU de GRENOBLE ALPES, Grenoble, Alpes, France

Study Investigating the Association of NP137 With mFOLFIRINOX in Locally Advanced Pancreatic Ductal Adenocarcinoma

Phase 1
Active, not recruiting
Conditions
Pancreatic Ductal Adenocarcinoma
Interventions
First Posted Date
2022-09-21
Last Posted Date
2025-04-18
Lead Sponsor
University Hospital, Grenoble
Target Recruit Count
43
Registration Number
NCT05546853
Locations
🇫🇷

CHU de GRENOBLE ALPES, Grenoble, Alpes, France

🇫🇷

CHU de BORDEAUX, Bordeaux, France

🇫🇷

CHRU Lille, Lille, France

and more 6 locations

GYNecological Cancers Treated with NETrin MAbs in Combination with Chemotherapy and /or Pembrolizumab

Phase 1
Active, not recruiting
Conditions
Endometrial Carcinoma
Cervix Carcinoma
Interventions
First Posted Date
2020-12-03
Last Posted Date
2024-10-08
Lead Sponsor
NETRIS Pharma
Target Recruit Count
240
Registration Number
NCT04652076
Locations
🇫🇷

Hopital de la Croix Saint Simon, Paris, France

🇫🇷

Institut Curie (Site Saint Cloud), Paris, France

🇫🇷

Institut Gustave Roussy, Paris, France

and more 11 locations
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