MedPath

Flecainide

Generic Name
Flecainide
Brand Names
Tambocor
Drug Type
Small Molecule
Chemical Formula
C17H20F6N2O3
CAS Number
54143-55-4
Unique Ingredient Identifier
K94FTS1806

Overview

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter. Flecainide was granted FDA approval on 31 October 1985.

Background

Flecainide is a Class I anti-arrhythmic agent like encainide and propafenone. Flecainide’s development began in 1966 and was first synthesized in 1972 as an attempt to generate new anesthetics. It is used to prevent supraventricular and ventricular arrhythmias, as well as paroxysmal atrial fibrillation and flutter. Flecainide was granted FDA approval on 31 October 1985.

Indication

In New Zealand and America, flecainide is indicated to prevent supraventricular arrhythmias and ventricular arrhythmias. In the United States, it is also indicated to prevent paroxysmal atrial fibrillation and flutter.

Associated Conditions

  • Atrial Fibrillation
  • Ventricular Tachycardia (VT)
  • Severe Atrioventricular nodal reentrant tachycardia
  • Severe Paroxysmal atrial fibrillation
  • Severe Paroxysmal supraventricular tachycardia
  • Severe Supraventricular Tachycardias
  • Severe Sustained ventricular tachycardia
  • Severe ventricular arrhythmias

FDA Approved Products

Flecainide Acetate
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:50 mg in 1 1
Approved: 2017/08/16
NDC:50090-6035
Flecainide Acetate
Manufacturer:Epic Pharma, LLC
Route:ORAL
Strength:150 mg in 1 1
Approved: 2024/03/26
NDC:42806-819
Flecainide Acetate
Manufacturer:A-S Medication Solutions
Route:ORAL
Strength:50 mg in 1 1
Approved: 2020/11/11
NDC:50090-5306
Flecainide Acetate
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:ORAL
Strength:150 mg in 1 1
Approved: 2023/06/02
NDC:0054-0012
Flecainide Acetate
Manufacturer:Hikma Pharmaceuticals USA Inc.
Route:ORAL
Strength:50 mg in 1 1
Approved: 2023/06/02
NDC:0054-0010

Singapore Approved Products

JAMP FLECAINIDE ACETATE TABLETS USP 100 MG
Manufacturer:Aizant Drug Research Solutions Pvt. Ltd.
Form:TABLET
Strength:100mg
Online:Yes
Approved: 2023/07/18
Approval:SIN16823P
TAMBOCOR TABLET 100 mg
Manufacturer:Unique Pharmaceutical Laboratories, (A Division of J.B. Chemicals & Pharmaceuticals Limited)
Form:TABLET
Strength:100 mg
Online:Yes
Approved: 1988/06/09
Approval:SIN01726P

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