Emicizumab

Generic Name
Emicizumab
Brand Names
Hemlibra
Drug Type
Biotech
Chemical Formula
-
CAS Number
1610943-06-0
Unique Ingredient Identifier
7NL2E3F6K3
Background

Emicizumab is a humanized recombinant monoclonal antibody that mimics the function of the coagulation Factor VIII and it has the capacity to bind simultaneously to activated Factor IX and Factor X. The ability of Emicizumab to bind to all these three different factors allows it to overcome immunogenicity and unstable hemostatic efficacy produced by previous ...

Indication

The main function of Emicizumab is the prevention of bleeding episodes. Thus, Emicizumab is approved for the routine prophylaxis to prevent or reduce the frequency of bleeding episodes of adult and pediatric patients with hemophilia A with or without Factor VIII inhibitors.
...

Associated Conditions
Bleeding caused by Hemophilia A
Associated Therapies
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ajmc.com
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Next-Gen Hemophilia Treatments Offer Hope for Joint Health, but Accessibility Challenges Remain

Hemophilia care must focus on joint health, health equity, and innovative therapies, especially for underserved populations. Despite advancements like extended half-life products, joint damage persists, and high costs limit access. Emerging therapies aim to reduce bleeding and improve outcomes, but disparities remain, particularly in low-resource settings. Precision medicine and future therapeutics, including gene therapy, offer hope for better, more equitable care.
ajmc.com
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HSSP Pharmacists Demonstrate Substantial Cost Avoidance in Specialty Medication Use

Pharmacist interventions in specialty medication management at Vanderbilt Health saved $129,705 to $162,133 monthly. The study, presented at AMCP Nexus, focused on discontinuations, dose adjustments, and therapeutic switches, with significant savings in medications like Emicizumab-kxwh and Ustekinumab. Pharmacists' roles in cost avoidance and patient management were highlighted, suggesting expanded roles in specialty settings.
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