Nebivolol

Generic Name
Nebivolol
Brand Names
Bystolic
Drug Type
Small Molecule
Chemical Formula
C22H25F2NO4
CAS Number
118457-14-0
Unique Ingredient Identifier
030Y90569U
Background

Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than atenolol, propranolol, or pindolol. Nebivolol and other beta blockers are generally not first l...

Indication

Nebivolol is indicated to treat hypertension.

Associated Conditions
Hypertension
Associated Therapies
-

Efficacy of Targeted Medical Therapy in Angina and Nonobstructive Coronary Arteries

First Posted Date
2024-05-22
Last Posted Date
2024-11-27
Lead Sponsor
Stanford University
Target Recruit Count
150
Registration Number
NCT06424834
Locations
🇺🇸

Stanford Hospital, Palo Alto, California, United States

Beta-blockade in Unruptured Intracranial Aneurysm

Phase 4
Not yet recruiting
Conditions
Interventions
First Posted Date
2024-02-08
Last Posted Date
2024-02-08
Lead Sponsor
Jagiellonian University
Target Recruit Count
100
Registration Number
NCT06249802
Locations
🇵🇱

University Hospital in Krakow, Kraków, Lesser Poland, Poland

Determination of Drug Levels for Pharmacotherapy of Heart Failure

First Posted Date
2023-09-13
Last Posted Date
2024-01-18
Lead Sponsor
University Hospital Ostrava
Target Recruit Count
100
Registration Number
NCT06035978
Locations
🇨🇿

University Hospital Ostrava, Ostrava, Czech Republic, Czechia

Cardioprotective Effects of Nebivolol Versus Placebo in Patients Undergoing Chemotherapy With Anthracyclines

First Posted Date
2023-02-15
Last Posted Date
2023-02-23
Lead Sponsor
Giulio Stefanini
Target Recruit Count
80
Registration Number
NCT05728632
Locations
🇮🇹

IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy

Effectiveness and Safety of Combination of Nebivolol and Amlodipine in Hypertensive Patients Versus Each Monotherapy

Phase 4
Completed
Conditions
Interventions
First Posted Date
2022-08-24
Last Posted Date
2023-03-01
Lead Sponsor
Menarini International Operations Luxembourg SA
Target Recruit Count
291
Registration Number
NCT05513937
Locations
🇧🇬

Medical Center Hera EOOD, Sofia, Bulgaria

Effect of Different Antihypertensive Drugs on Central Blood Pressure

Not Applicable
Active, not recruiting
Conditions
Interventions
First Posted Date
2022-04-14
Last Posted Date
2022-04-14
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
110
Registration Number
NCT05328310
Locations
🇰🇷

Korea University Anam Hospital, Seoul, Korea, Republic of

24 Hour Ambulatory Cardiac Oxygen Consumption

First Posted Date
2021-12-27
Last Posted Date
2021-12-27
Lead Sponsor
State University of New York at Buffalo
Target Recruit Count
26
Registration Number
NCT05170061
Locations
🇺🇸

Erie County Medical Center, Buffalo, New York, United States

To Evaluate Drug-drug Interactions Between DWN12088 and Nebivolol or Paroxetine in Healthy Volunteers

First Posted Date
2021-05-17
Last Posted Date
2021-08-04
Lead Sponsor
Daewoong Pharmaceutical Co. LTD.
Target Recruit Count
24
Registration Number
NCT04888728
Locations
🇰🇷

Inje University Busan Paik Hospital, Busan, Korea, Republic of

Efficacy of Medical Therapy in Women and Men With Angina and Myocardial Bridging

First Posted Date
2019-10-17
Last Posted Date
2023-11-29
Lead Sponsor
Stanford University
Target Recruit Count
360
Registration Number
NCT04130438
Locations
🇺🇸

Stanford University, Stanford, California, United States

The Effect of Nebivolol in Hypertensive Patients With Coronary Arterial Spasm

First Posted Date
2019-04-29
Last Posted Date
2020-03-10
Lead Sponsor
Korea University Anam Hospital
Target Recruit Count
51
Registration Number
NCT03930433
Locations
🇰🇷

Korea University Anam Hospital, Seoul, Korea, Republic of

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