Clonidine
- Generic Name
- Clonidine
- Brand Names
- Catapres, Catapres-TTS, Catapres-tts-1, Duraclon, Kapvay, Nexiclon XR
- Drug Type
- Small Molecule
- Chemical Formula
- C9H9Cl2N3
- CAS Number
- 4205-90-7
- Unique Ingredient Identifier
- MN3L5RMN02
Overview
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD. Clonidine was granted FDA approval on 3 September 1974.
Background
Clonidine is an imidazole derivate that acts as an agonist of alpha-2 adrenoceptors. This activity is useful for the treatment of hypertension, severe pain, and ADHD. Clonidine was granted FDA approval on 3 September 1974.
Indication
Clonidine tablets and transdermal systems are indicated for the treatment of hypertension alone or in combination with other medications. A clonidine injection is indicated for use with opiates in the treatment of severe cancer pain where opiates alone are insufficient. An extended release tablet of clonidine is indicated for the treatment of ADHD either alone or in combination with other medications. Clonidine is also used for the diagnosis of pheochromocytoma, treatment of nicotine dependance, and opiate withdrawal.
Associated Conditions
- Attention Deficit Hyperactivity Disorder (ADHD)
- Defiant Disorder, Oppositional
- Gilles de la Tourette's Syndrome
- Hot Flashes
- Human Growth Hormone Deficiency
- Hypertension
- Opioid Withdrawal (Disorder)
- Pheochromocytoma
- Postherpetic Neuralgia
- Sialorrhea caused by clozapine
- Diabetic diarrhea
- Methadone withdrawal
- Severe Cancer pain
Clinical Trials
FDA Approved Products
Singapore Approved Products
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