Lipoic acid

Generic Name
Lipoic acid
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C8H14O2S2
CAS Number
1200-22-2
Unique Ingredient Identifier
VLL71EBS9Z
Background

A vitamin-like antioxidant.

Indication

For nutritional supplementation, also for treating dietary shortage or imbalance.

Associated Conditions
Diabetic Neuropathies, Type 2 Diabetes Mellitus
Associated Therapies
Dietary and Nutritional Therapies, Nutritional supplementation

Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Diabetic Polyneuropathy (Stage 1 or 2)

Phase 3
Completed
Conditions
Interventions
First Posted Date
2009-09-15
Last Posted Date
2022-02-07
Lead Sponsor
MEDA Pharma GmbH & Co. KG
Target Recruit Count
460
Registration Number
NCT00977483
Locations
🇺🇸

Mayo Clinic Arizona, Scottsdale, Arizona, United States

🇳🇱

University Hospital Utrecht Department of Internal Medicine, Utrecht, Netherlands

🇺🇸

Loyola University Medical Center, Maywood, Illinois, United States

and more 35 locations

Lipoic Acid to Treat Chronic Inflammatory Demyelinating Polyneuropathy

First Posted Date
2009-08-20
Last Posted Date
2020-08-19
Lead Sponsor
Oregon Health and Science University
Target Recruit Count
7
Registration Number
NCT00962429
Locations
🇺🇸

Oregon Health & Science University, Portland, Oregon, United States

Effect of Long Term α-Lipoic Acid Treatment on Endothelial Function in Patients With Type 2 Diabetes

Phase 2
Completed
Conditions
First Posted Date
2007-06-25
Last Posted Date
2018-03-20
Lead Sponsor
Medical University of Vienna
Target Recruit Count
30
Registration Number
NCT00490867

Alpha-Lipoic Acid in Preventing Hearing Loss in Cancer Patients Undergoing Treatment With Cisplatin

First Posted Date
2007-05-24
Last Posted Date
2014-03-07
Lead Sponsor
US Department of Veterans Affairs
Target Recruit Count
39
Registration Number
NCT00477607
Locations
🇺🇸

Oregon Health & Science University, Portland, Oregon, United States

🇺🇸

VA Medical Center, Portland, Portland, Oregon, United States

The Effects of Lipoic Acid on Glycaemic Control in Type 2 Diabetes

Phase 2
Withdrawn
Conditions
Interventions
First Posted Date
2006-11-14
Last Posted Date
2024-05-29
Lead Sponsor
University of Edinburgh
Registration Number
NCT00398892
Locations
🇬🇧

Diabetes Department, St John's Hospital, Livingston, Scotland, United Kingdom

Assessment of Efficacy and Safety of Thioctic Acid in the Oral Treatment of Symptomatic Diabetic Neuropathy (SYDNEY 2)

Phase 3
Completed
Conditions
First Posted Date
2006-05-22
Last Posted Date
2022-02-07
Lead Sponsor
MEDA Pharma GmbH & Co. KG
Target Recruit Count
170
Registration Number
NCT00328601
Locations
🇷🇺

Chair of Nervous Diseases of IM Sechenov Moscow Medical Academy at City Clinical Hospital, Moscow, Russian Federation

🇮🇱

Haddassah Medical Center Ein Kerem, Diabetes Unit, Jerusalem, Israel

🇷🇺

Chair of Endocrinology and Diabetology of Russian Medical Academy of Postgraduate Education at Central Clinical Hospital of Ministry of Communication RF, Moscow, Russian Federation

and more 2 locations

Tocopherols and Alpha Lipoic Acid Treatment Chronic Kidney Disease (TALAT)

First Posted Date
2006-03-30
Last Posted Date
2009-07-09
Lead Sponsor
Vanderbilt University
Target Recruit Count
62
Registration Number
NCT00308971
Locations
🇺🇸

Maine Medical Center, Portland, Maine, United States

🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Provision of Antioxidant Therapy in Hemodialysis (PATH) Study

First Posted Date
2005-10-12
Last Posted Date
2012-01-11
Lead Sponsor
Vanderbilt University
Target Recruit Count
385
Registration Number
NCT00237718
Locations
🇺🇸

Fresenius Medical Care North America, Nashville, Tennessee, United States

Cardiovascular Disease (CVD) Risk and Prevention in Early Glucose Intolerance

First Posted Date
2005-07-22
Last Posted Date
2013-12-05
Lead Sponsor
Emory University
Target Recruit Count
84
Registration Number
NCT00122447
Locations
🇺🇸

Emory University Hospital, Atlanta, Georgia, United States

🇺🇸

Grady Health System, Atlanta, Georgia, United States

Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer

First Posted Date
2005-06-03
Last Posted Date
2014-04-08
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
244
Registration Number
NCT00112996
Locations
🇺🇸

Hembree Mercy Cancer Center at St. Edward Mercy Medical Center, Fort Smith, Arkansas, United States

🇺🇸

Cancer Research for the Ozarks, Springfield, Missouri, United States

🇺🇸

CCOP - Scott and White Hospital, Temple, Texas, United States

and more 10 locations
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