Lipoic acid
- Generic Name
- Lipoic acid
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14O2S2
- CAS Number
- 1200-22-2
- Unique Ingredient Identifier
- VLL71EBS9Z
- Background
A vitamin-like antioxidant.
- Indication
For nutritional supplementation, also for treating dietary shortage or imbalance.
- Associated Conditions
- Diabetic Neuropathies, Type 2 Diabetes Mellitus
- Associated Therapies
- Dietary and Nutritional Therapies, Nutritional supplementation
Metabolic and Clinical Effect of Alpha-lipoic Acid Administration in Schizophrenic Subjects
Not Applicable
Completed
- Conditions
- Metabolic EvaluationCardiac Complications
- Interventions
- First Posted Date
- 2025-03-25
- Last Posted Date
- 2025-03-27
- Lead Sponsor
- University of Messina
- Target Recruit Count
- 15
- Registration Number
- NCT06787781
- Locations
- 🇮🇹
University of Messina, Messina, Italy
Prevention of Doxorubicin-induced Cardiotoxicity in Breast Cancer Patients
- First Posted Date
- 2024-11-25
- Last Posted Date
- 2024-11-25
- Lead Sponsor
- British University In Egypt
- Target Recruit Count
- 80
- Registration Number
- NCT06703593
- Locations
- 🇪🇬
The British University in Egypt, Cairo, El-Sherouk City, Egypt
Effect of ALA Combined with Letrozole on Polycystic Ovary Syndrome Clinical Outcome in Infertile Females
Phase 3
Recruiting
- Conditions
- Infertility, FemalePolycystic Ovary Syndrome
- Interventions
- First Posted Date
- 2024-05-17
- Last Posted Date
- 2025-02-24
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 150
- Registration Number
- NCT06418347
- Locations
- 🇪🇬
Ain shams university, Cairo, Egypt
Alpha Lipoic Acid in Pediatrics on Hemodialysis
Phase 3
- Conditions
- Hemodialysis ComplicationPediatric Kidney DiseaseCardiovascular Complication
- Interventions
- Other: Placebo
- First Posted Date
- 2024-02-29
- Last Posted Date
- 2025-04-16
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 50
- Registration Number
- NCT06286098
- Locations
- 🇪🇬
New Pediatrics Hospital, Faculty of Medicine, Ain Shams University, Cairo, El Weili, Egypt
Caffeine vs. ALA in BMS Treatment. (BMS: Burning Mouth Syndrome. ALA: Alpha-Lipoic Acid.)
Not Applicable
Completed
- Conditions
- CaffeineBurning Mouth Syndrome
- Interventions
- Dietary Supplement: Caffeine
- First Posted Date
- 2024-01-08
- Last Posted Date
- 2024-01-08
- Lead Sponsor
- Lu Jiang
- Target Recruit Count
- 130
- Registration Number
- NCT06195137
- Locations
- 🇨🇳
West China Hospital of Stomatology, Sichuan University, Chengdu, China
Assessment of Antioxidant Therapy on Oxidative Stress Biomarkers in Type 2 Diabetic Patients With Neuropathy
Phase 2
Completed
- Conditions
- Peripheral Diabetic Neuropathy
- Interventions
- Drug: Super Oxide DismutaseDrug: Resveratrol, Alpha lipoic acid, Super oxide dismutase
- First Posted Date
- 2023-11-14
- Last Posted Date
- 2024-08-26
- Lead Sponsor
- Khyber Medical University Peshawar
- Target Recruit Count
- 100
- Registration Number
- NCT06131918
- Locations
- 🇵🇰
Syed Hamid Habib, Peshawar, KPK, Pakistan
Alpha-Lipoic Acid in Patients With Sepsis
- First Posted Date
- 2023-04-12
- Last Posted Date
- 2023-04-12
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 60
- Registration Number
- NCT05808946
- Locations
- 🇪🇬
Ain Shams University Specialized Hospital, Cairo, Egypt
Trial of the Combination of Alpha-Lipoic Acid and Mirabegron in Women and in Men With Obesity
Phase 2
Not yet recruiting
- Conditions
- Insulin ResistanceObesity
- Interventions
- First Posted Date
- 2023-02-06
- Last Posted Date
- 2025-05-21
- Target Recruit Count
- 60
- Registration Number
- NCT05713799
- Locations
- 🇺🇸
National Institutes of Health Clinical Center, Bethesda, Maryland, United States
Clinical Study Evaluating the Safety and Efficacy of Roflumilast in Type 2 Diabetic Patients With Diabetic Neuropathy
Phase 3
Completed
- Conditions
- Type 2 Diabetes (Adult Onset)Diabetic Neuropathies
- Interventions
- First Posted Date
- 2022-05-11
- Last Posted Date
- 2023-11-22
- Lead Sponsor
- Tanta University
- Target Recruit Count
- 60
- Registration Number
- NCT05369793
- Locations
- 🇪🇬
Asmaa Elshafey Elsharab, Tanta, Egypt
A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients
Phase 4
Completed
- Conditions
- Antioxidative StressEnd Stage Renal Disease on Dialysis
- Interventions
- First Posted Date
- 2022-03-04
- Last Posted Date
- 2022-03-04
- Lead Sponsor
- Ain Shams University
- Target Recruit Count
- 68
- Registration Number
- NCT05266794
- Locations
- 🇪🇬
Ain Shams University, Cairo, Egypt
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