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Lipoic acid

Generic Name
Lipoic acid
Drug Type
Small Molecule
Chemical Formula
C8H14O2S2
CAS Number
1200-22-2
Unique Ingredient Identifier
VLL71EBS9Z
Background

A vitamin-like antioxidant.

Indication

For nutritional supplementation, also for treating dietary shortage or imbalance.

Associated Conditions
Diabetic Neuropathies, Type 2 Diabetes Mellitus
Associated Therapies
Dietary and Nutritional Therapies, Nutritional supplementation
Clinical Trials
Related News

Alpha-Lipoic Acid in Preventing Peripheral Neuropathy in Patients Receiving Chemotherapy for Cancer

Phase 3
Completed
Conditions
Neurotoxicity
Unspecified Childhood Solid Tumor, Protocol Specific
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
Other: placebo
First Posted Date
2005-06-03
Last Posted Date
2014-04-08
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
244
Registration Number
NCT00112996
Locations
🇺🇸

Hembree Mercy Cancer Center at St. Edward Mercy Medical Center, Fort Smith, Arkansas, United States

🇺🇸

Cancer Research for the Ozarks, Springfield, Missouri, United States

🇺🇸

CCOP - Scott and White Hospital, Temple, Texas, United States

and more 10 locations

Painful HIV Neuropathy and Alpha-Lipoic Acid

Phase 1
Completed
Conditions
HIV
Peripheral Neuropathy
First Posted Date
2004-03-16
Last Posted Date
2008-04-22
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Target Recruit Count
60
Registration Number
NCT00079807
Locations
🇺🇸

University of North Carolina Chapel Hill, Chapel Hill, North Carolina, United States

Antioxidant Functions of Lipoic Acid

Phase 2
Completed
Conditions
Hypercholesterolemia
First Posted Date
2003-07-31
Last Posted Date
2007-10-02
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Target Recruit Count
16
Registration Number
NCT00065624
Locations
🇺🇸

Vanderbilt University Medical Center, Nashville, Tennessee, United States

Immune Restoration by Lipoic Acid in AIDS

Phase 2
Completed
Conditions
Acquired Immunodeficiency Syndrome
HIV Infections
First Posted Date
2002-04-09
Last Posted Date
2006-08-18
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Target Recruit Count
33
Registration Number
NCT00033176
Locations
🇺🇸

Quest Clinical Research, San Francisco, California, United States

🇺🇸

Eye Clinic, Santa Clara Valley Medical Center, San Jose, California, United States

A Study of Thioctic Acid and Deprenyl in HIV-Infected Patients With Dementia

Phase 2
Completed
Conditions
Cognitive Disorders
HIV Infections
First Posted Date
2001-08-31
Last Posted Date
2005-06-24
Lead Sponsor
The Dana Foundation
Target Recruit Count
32
Registration Number
NCT00002154
Locations
🇺🇸

Univ of Rochester Med Ctr, Rochester, New York, United States

🇺🇸

Johns Hopkins Hosp, Baltimore, Maryland, United States

🇺🇸

Columbia Univ, New York, New York, United States

Natural Antioxidants in the Treatment of Multiple Sclerosis

Phase 1
Completed
Conditions
Multiple Sclerosis
First Posted Date
2001-02-05
Last Posted Date
2006-08-18
Lead Sponsor
National Center for Complementary and Integrative Health (NCCIH)
Registration Number
NCT00010842
Locations
🇺🇸

Oregon Health Sciences University, Portland, Oregon, United States

Pilot Compassionate Use Study of Thioctic Acid Treatment in Mitochondrial Myopathy

Not Applicable
Completed
Conditions
Mitochondrial Myopathy
First Posted Date
2000-02-25
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
1
Registration Number
NCT00004770
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