Lipoic acid
- Generic Name
- Lipoic acid
- Drug Type
- Small Molecule
- Chemical Formula
- C8H14O2S2
- CAS Number
- 1200-22-2
- Unique Ingredient Identifier
- VLL71EBS9Z
- Background
A vitamin-like antioxidant.
- Indication
For nutritional supplementation, also for treating dietary shortage or imbalance.
- Associated Conditions
- Diabetic Neuropathies, Type 2 Diabetes Mellitus
- Associated Therapies
- Dietary and Nutritional Therapies, Nutritional supplementation
Alpha Lipoic Acid and Diabetes Mellitus: Potential Effects on Peripheral Neuropathy
- Conditions
- Diabetes Mellitus, Type 2Diabetic Polyneuropathy
- Interventions
- First Posted Date
- 2020-03-26
- Last Posted Date
- 2020-12-30
- Lead Sponsor
- Benha University
- Target Recruit Count
- 90
- Registration Number
- NCT04322240
- Locations
- 🇪🇬
Benha University Hospital, Banhā, Qalubiya, Egypt
Alpha Lipoic Acid to Decrease Pain and Side Effects in Concurrent Treatment of HNSCC
- First Posted Date
- 2019-08-02
- Last Posted Date
- 2024-03-21
- Lead Sponsor
- University of Colorado, Denver
- Target Recruit Count
- 5
- Registration Number
- NCT04042935
- Locations
- 🇺🇸
University of Colorado Hospital, Aurora, Colorado, United States
Impact of Lipoic Acid Use on Stroke Outcome After Reperfusion Therapy in Patients With Diabetes (IMPORTANT)
- First Posted Date
- 2019-08-01
- Last Posted Date
- 2019-08-02
- Lead Sponsor
- Chonnam National University Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT04041167
- Locations
- 🇰🇷
Chonnam National University Hospital, Gwangju, Korea, Republic of
Alpha-lipoic Acid Adjunctive Therapy in Schizophrenia
- Conditions
- Oxidative StressSchizophrenia
- Interventions
- Drug: Placebo Oral Tablet
- First Posted Date
- 2018-12-28
- Last Posted Date
- 2022-08-29
- Lead Sponsor
- Nucleo De Pesquisa E Desenvolvimento De Medicamentos Da Universidade Federal Do Ceara
- Target Recruit Count
- 48
- Registration Number
- NCT03788759
- Locations
- 🇧🇷
Núcleo de Pesquisa e Desenvolvimento de Medicamentos - UFC, Fortaleza, CE, Brazil
Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis
- Conditions
- Multiple SclerosisProgressive Multiple SclerosisSecondary Progressive Multiple SclerosisPrimary Progressive Multiple Sclerosis
- Interventions
- First Posted Date
- 2018-04-11
- Last Posted Date
- 2019-03-22
- Lead Sponsor
- Rebecca Spain
- Target Recruit Count
- 20
- Registration Number
- NCT03493841
- Locations
- 🇺🇸
Oregon Health & Science University, Portland, Oregon, United States
Lipoic Acid for Progressive Multiple Sclerosis (MS)
- First Posted Date
- 2017-05-19
- Last Posted Date
- 2025-03-03
- Lead Sponsor
- VA Office of Research and Development
- Target Recruit Count
- 115
- Registration Number
- NCT03161028
- Locations
- 🇺🇸
VA Puget Sound Health Care System Seattle Division, Seattle, WA, Seattle, Washington, United States
🇺🇸Washington DC VA Medical Center, Washington, DC, Washington, District of Columbia, United States
🇺🇸VA North Texas Health Care System Dallas VA Medical Center, Dallas, TX, Dallas, Texas, United States
Effects of Alpha-acid Lipoic in PCOS Women
- First Posted Date
- 2016-01-28
- Last Posted Date
- 2016-01-28
- Lead Sponsor
- Catholic University of the Sacred Heart
- Target Recruit Count
- 40
- Registration Number
- NCT02666170
Alpha Lipoic Acid in Geographic Atrophy
- Conditions
- Age-Related Macular Degeneration
- Interventions
- Drug: Placebo
- First Posted Date
- 2015-11-24
- Last Posted Date
- 2020-08-06
- Lead Sponsor
- University of Pennsylvania
- Target Recruit Count
- 68
- Registration Number
- NCT02613572
- Locations
- 🇺🇸
Scheie Eye Institute of the University of Pennsylvania, Philadelphia, Pennsylvania, United States
🇺🇸University of Iowa Hospitals and Clinics, Department of Ophthalmology & Visual Sciences, Iowa City, Iowa, United States
🇺🇸NJ Retina, Teaneck, New Jersey, United States
Alpha Lipoic Acid for Treatment of Diabetic Neuropathy
- First Posted Date
- 2015-05-12
- Last Posted Date
- 2016-03-02
- Lead Sponsor
- Universidad Popular Autónoma del Estado de Puebla
- Target Recruit Count
- 45
- Registration Number
- NCT02439879
Alpha Lipoic Acid on Clinical and Electrophysiological Recovery in Carpal Tunnel Syndrome Undergoing Surgical Release
- First Posted Date
- 2015-03-06
- Last Posted Date
- 2016-08-09
- Lead Sponsor
- Hospital Civil de Guadalajara
- Target Recruit Count
- 40
- Registration Number
- NCT02382328
- Locations
- 🇲🇽
Antiguo Hospital Civil de Guadalajara Fray Antonio Alcalde, Guadalajara, Jalisco, Mexico
Drug Development Updates
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