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Selenious acid

Generic Name
Selenious acid
Brand Names
Multitrace-5, Multrys
Drug Type
Small Molecule
Chemical Formula
H2O3Se
CAS Number
7783-00-8
Unique Ingredient Identifier
F6A27P4Q4R
Background

Selenious acid is the acid form of sodium selenite, a form of selenium .

Selenium is an essential trace element and antioxidant. It is a cofactor metabolic enzyme regulation. It also plays an important role in maintaining the general health of tissue and muscle and has antioxidant properties. Selenium is a component of glutathione peroxidase enzyme, which protects cell components from oxidative damage due to peroxides produced during cellular metabolism .

Selenium (Se) has been demonstrated to prevent cancer in numerous animal models when administered selenium at levels exceeding the nutritional requirements. One study showed efficacy in the prevention of malignancy while utilizing a selenium supplement in humans. The reports from such studies have heightened the interest in additional human selenium supplementation studies to validate the results in larger populations .

Interestingly, selenium is being studied as a potential therapy in the prevention or management of atherosclerosis .

Indication

Selenium injection is indicated for use as a supplement to intravenous solutions given for total parenteral nutrition (TPN). Administration of selenious acid in TPN formulas helps to maintain plasma selenium levels and also to maintain endogenous stores to prevent deficiency .

Selenium compounds, such as selenium sulfide, are used topically in anti-dandruff shampoos and in cases of seborrhea .

For the purpose of brevity, selenite will the focus of discussion, and more information about selenium can be obtained at Selenium.

Associated Conditions
Selenium Deficiency
Associated Therapies
Parenteral Nutrition, Selenium Supplementation

Evaluate the Efficacy of Selenium for the Prevention of Chemotherapy-induced Mucositis During Autologous Stem Cell Transplantation.

Phase 3
Completed
Conditions
Mucositis Oral
Stem Cell Transplant Complications
Interventions
Drug: Placebos
Drug: Selenium
First Posted Date
2019-09-06
Last Posted Date
2024-12-30
Lead Sponsor
University Hospital, Angers
Target Recruit Count
100
Registration Number
NCT04080622
Locations
🇫🇷

CHU Angers, Angers, Maine et Loire, France

TB Nutrition, Immunology and Epidemiology

Phase 3
Completed
Conditions
Mycobacterium Tuberculosis
First Posted Date
2005-09-15
Last Posted Date
2010-08-27
Lead Sponsor
National Institute of Allergy and Infectious Diseases (NIAID)
Target Recruit Count
887
Registration Number
NCT00170404
Locations
🇹🇿

Muhimbili University, College of Health Sciences, Dar Es Salaam, Tanzania

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