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Centhaquine

Generic Name
Centhaquine
Drug Type
Small Molecule
Chemical Formula
C22H25N3
CAS Number
57961-90-7
Unique Ingredient Identifier
QD4VI0J9T5
Background

Centhaquine is under investigation in clinical trial NCT04045327 (Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock).

A Study to Assess the Safety and Efficacy of Centhaquine in Hypovolemic Shock Patients

Phase 4
Recruiting
Conditions
Hypovolemic Shock
Interventions
First Posted Date
2023-07-21
Last Posted Date
2025-05-13
Lead Sponsor
Pharmazz, Inc.
Target Recruit Count
400
Registration Number
NCT05956418
Locations
🇮🇳

KG Hospital, Coimbatore, Tamil Nadu, India

🇮🇳

Aman Hospital, Vadodara, Gujarat, India

🇮🇳

Dayanand Medical College & Hospital (DMCH), Ludhiāna, Punjab, India

and more 14 locations

A Study to Assess Safety and Efficacy of Centhaquine as a Resuscitative Agent

Phase 3
Not yet recruiting
Conditions
Hypovolemic Shock
Interventions
Drug: Normal Saline
First Posted Date
2022-02-22
Last Posted Date
2023-06-22
Lead Sponsor
Pharmazz, Inc.
Target Recruit Count
430
Registration Number
NCT05251181

Multicentric, Randomized Study to Assess Safety and Efficacy of Centhaquine in COVID-19 Patients With ARDS

Phase 2
Not yet recruiting
Conditions
COVID-19 Acute Respiratory Distress Syndrome
Interventions
Drug: Normal Saline
First Posted Date
2022-02-15
Last Posted Date
2023-06-22
Lead Sponsor
Pharmazz, Inc.
Target Recruit Count
60
Registration Number
NCT05241067

PMZ-2010 (Centhaquine) as a Resuscitative Agent for Hypovolemic Shock

Phase 2
Completed
Conditions
Blood Loss
Hypovolemic Shock
Interventions
Drug: Normal Saline
First Posted Date
2019-08-14
Last Posted Date
2019-08-14
Lead Sponsor
Pharmazz, Inc.
Target Recruit Count
50
Registration Number
NCT04056065
Locations
🇮🇳

KLE's Dr. Prabhakar Kore Hospital & Medical Research Centre, Belgaum, India

🇮🇳

Dayanand Medical College & Hospital, Ludhiana, India

🇮🇳

ORIANA Hospital, Varanasi, India

and more 4 locations

Efficacy of PMZ-2010 (Centhaquine) a Resuscitative Agent for Hypovolemic Shock

Phase 3
Completed
Conditions
Hypovolemic Shock
Interventions
Drug: Normal saline + Standard Treatment
First Posted Date
2019-08-05
Last Posted Date
2019-10-04
Lead Sponsor
Pharmazz, Inc.
Target Recruit Count
105
Registration Number
NCT04045327
Locations
🇮🇳

Seven Star Hospital, Nagpur, Maha, India

🇮🇳

Radiant Superspeciality Hospital, Amravati, India

🇮🇳

ACSR Government Medical College & Hospital, Nellore, India

and more 15 locations
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