Nesiritide
- Generic Name
- Nesiritide
- Brand Names
- -
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 124584-08-3
- Unique Ingredient Identifier
- P7WI8UL647
- Background
Nesiritide is a medication used to treat acutely decompensated congestive heart failure with dyspnea at rest or with minimal exertion (such as talk, eating or bathing). Nesiritide is a 32 amino acid recombinant human B-type natriuretic peptide.
- Indication
适用于急性代偿性心力衰竭、慢性失代偿性心力衰竭、心肌梗死、心脏导管手术等。由于静脉使用起效快，更适用于急性心力衰竭。
- Associated Conditions
- Acute Decompensated Heart Failure (ADHF)
- Associated Therapies
- -
Clinical Study to Evaluate Nesiritide in Patients Undergoing Coronary Artery Bypass Graft (CABG) Surgery A014 / NAPA
- First Posted Date
- 2008-04-04
- Last Posted Date
- 2011-05-19
- Lead Sponsor
- Scios, Inc.
- Target Recruit Count
- 305
- Registration Number
- NCT00653042
Nesiritide Therapy to Preserve Function of the Left Ventricle After Myocardial Infarction
- First Posted Date
- 2007-12-14
- Last Posted Date
- 2014-09-09
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 59
- Registration Number
- NCT00573144
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Role of Natriuretic Peptides in the Treatment of Acutely Decompensated Heart Failure Patient With Obstructive Airways Disease
- First Posted Date
- 2007-11-22
- Last Posted Date
- 2015-06-25
- Lead Sponsor
- The Alfred
- Target Recruit Count
- 6
- Registration Number
- NCT00562692
- Locations
- 🇦🇺
Alfred Hospital, Melbourne, Victoria, Australia
Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery
- Conditions
- Interventions
- First Posted Date
- 2007-10-12
- Last Posted Date
- 2018-06-25
- Lead Sponsor
- John M Costello
- Target Recruit Count
- 106
- Registration Number
- NCT00543309
- Locations
- 🇺🇸
Children's Hospital Boston, Boston, Massachusetts, United States
An Efficacy and Safety Study for Nesiritide in Heart Failure Patients With Reduced Kidney Function Undergoing Coronary Artery Bypass Graft Surgery Requiring Cardiopulmonary Bypass (CPB Pump or Heart Lung Machine)
- First Posted Date
- 2007-09-17
- Last Posted Date
- 2016-09-20
- Lead Sponsor
- Scios, Inc.
- Registration Number
- NCT00530361
Double Blind Randomized Placebo Controlled Trial of Natrecor in Acute Decompensated Heart Failure With Normal EF
- Conditions
- Interventions
- Locations
- 🇺🇸
University of Medicine and Dentistry of New Jersey/ New Jersey Medical School, Newark, New Jersey, United States
A Study Testing the Effectiveness of Nesiritide in Patients With Acute Decompensated Heart Failure
- First Posted Date
- 2007-05-21
- Last Posted Date
- 2013-03-08
- Lead Sponsor
- Scios, Inc.
- Target Recruit Count
- 7141
- Registration Number
- NCT00475852
BNP Therapy Observation Unit Outcomes STudy (BOOST)
- First Posted Date
- 2007-03-29
- Last Posted Date
- 2015-02-09
- Lead Sponsor
- Emory University
- Target Recruit Count
- 17
- Registration Number
- NCT00453453
- Locations
- 🇺🇸
Grady Memorial Hosptial, Atlanta, Georgia, United States
Human B-type Natriuretic Peptide (BNP) (Nesiritide) to Help Heart, Kidney, and Hormonal Functions in Persons With Lower Heart Pumping Function
- Conditions
- Interventions
- First Posted Date
- 2006-11-30
- Last Posted Date
- 2014-03-17
- Lead Sponsor
- Mayo Clinic
- Target Recruit Count
- 37
- Registration Number
- NCT00405639
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Natriuretic Peptide System as Therapy in Human Preclinical Left Ventricle Dysfunction
- Conditions
- Interventions
- First Posted Date
- 2006-10-13
- Last Posted Date
- 2012-05-17
- Lead Sponsor
- Horng Chen
- Target Recruit Count
- 58
- Registration Number
- NCT00387621
- Locations
- 🇺🇸
Mayo Clinic, Rochester, Minnesota, United States
Drug Development Updates
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