AMG-404
- Generic Name
- AMG-404
AMG 757 and AMG 404 in Subjects With Small Cell Lung Cancer (SCLC)
- First Posted Date
- 2021-05-13
- Last Posted Date
- 2024-10-23
- Lead Sponsor
- Amgen
- Target Recruit Count
- 23
- Registration Number
- NCT04885998
- Locations
- 🇧🇪
Universitair Ziekenhuis Leuven - Campus Gasthuisberg, Leuven, Belgium
🇺🇸University of Kentucky, Lexington, Kentucky, United States
🇦🇹Universitaetsklinikum Allgemeines Krankenhaus Wien, Wien, Austria
Study of AMG 994 Monotherapy and AMG 994 and AMG 404 Combination Therapy in Participants With Advanced Solid Tumors
- First Posted Date
- 2021-01-27
- Last Posted Date
- 2025-01-06
- Lead Sponsor
- Amgen
- Target Recruit Count
- 11
- Registration Number
- NCT04727554
- Locations
- 🇦🇺
Linear Clinical Research Limited, Nedlands, Western Australia, Australia
🇺🇸Sarah Cannon Research Institute, Nashville, Tennessee, United States
🇺🇸University of Texas MD Anderson Cancer Center, Houston, Texas, United States
Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (mCRPC)
- Conditions
- Metastatic Castration-resistant Prostate Cancer
- Interventions
- First Posted Date
- 2020-11-17
- Last Posted Date
- 2024-08-29
- Lead Sponsor
- Amgen
- Target Recruit Count
- 65
- Registration Number
- NCT04631601
- Locations
- 🇺🇸
University of Alabama at Birmingham, Birmingham, Alabama, United States
🇺🇸University of California at Irvine Medical Center, Orange, California, United States
🇺🇸University of California San Francisco Mission Bay Campus, San Francisco, California, United States
Blinatumomab in Combination With AMG 404 for the Treatment of Adults With Relapsed or Refractory B Cell Precursor ALL
- Conditions
- Acute Lymphoblastic Leukemia
- Interventions
- First Posted Date
- 2020-08-24
- Last Posted Date
- 2024-04-08
- Lead Sponsor
- Amgen
- Target Recruit Count
- 17
- Registration Number
- NCT04524455
- Locations
- 🇫🇷
Centre Hospitalier Lyon Sud, Pierre Benite, France
🇪🇸Hospital Universitari Germans Trias i Pujol, Badalona, Cataluña, Spain
🇩🇪Universitätsklinikum Schleswig-Holstein, Kiel, Germany
Sotorasib Activity in Subjects With Advanced Solid Tumors With KRAS p.G12C Mutation (CodeBreak 101)
- Conditions
- Advanced Solid TumorsKirsten Rat Sarcoma (KRAS) pG12C Mutation
- Interventions
- Drug: IV Chemotherapy (Regimen 1)Drug: Carboplatin, pemetrexed, docetaxel, paclitaxelDrug: IV Chemotherapy (Regimen 2)
- First Posted Date
- 2019-12-04
- Last Posted Date
- 2025-03-27
- Lead Sponsor
- Amgen
- Target Recruit Count
- 1200
- Registration Number
- NCT04185883
- Locations
- 🇺🇸
Arizona Oncology Associates Professional Corporation, Tucson, Arizona, United States
🇺🇸City of Hope National Medical Center, Duarte, California, United States
🇺🇸University of California San Diego Moores Cancer Center, La Jolla, California, United States
AMG 404 in Patients With Advanced Solid Tumors
- First Posted Date
- 2019-02-25
- Last Posted Date
- 2024-12-13
- Lead Sponsor
- Amgen
- Target Recruit Count
- 171
- Registration Number
- NCT03853109
- Locations
- 🇵🇱
Narodowy Instytut Onkologii im Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy, Warszawa, Poland
🇰🇷Seoul National University Hospital, Seoul, Korea, Republic of
🇧🇷Instituto Coi, Rio de Janeiro, Brazil
Study of AMG 596 in Patients With EGFRvIII Positive Glioblastoma
- First Posted Date
- 2017-09-28
- Last Posted Date
- 2024-10-29
- Lead Sponsor
- Amgen
- Target Recruit Count
- 30
- Registration Number
- NCT03296696
- Locations
- 🇺🇸
University of California Los Angeles, Los Angeles, California, United States
🇳🇱Vrije Universiteit Medisch Centrum, Amsterdam, Netherlands
🇩🇪Universitaetsklinikum Wuerzburg, Würzburg, Germany
Drug Development Updates
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