MedPath

WX-216

Generic Name
WX-216

Pharmacokinetics of ZSP1273 in Participants With Severe Kidney Disease

Phase 1
Completed
Conditions
Kidney Impairment
Interventions
First Posted Date
2024-02-08
Last Posted Date
2025-03-19
Lead Sponsor
Guangdong Raynovent Biotech Co., Ltd
Target Recruit Count
16
Registration Number
NCT06248567
Locations
🇨🇳

The First Affiliated Hospital of Xiamen University, Xiamen, China

Pharmacokinetics of ZSP1273 in Elder Participants

Phase 1
Completed
Conditions
Elder
Interventions
First Posted Date
2023-12-05
Last Posted Date
2023-12-05
Lead Sponsor
Guangdong Raynovent Biotech Co., Ltd
Target Recruit Count
32
Registration Number
NCT06157450
Locations
🇨🇳

Sir Run Run Hospital, Nanjing, Jiangsu, China

Drug-durg Interaction of ZSP1273 With Digoxin, Rosuvastatin,Itraconazole and Probenecid

Phase 1
Completed
Conditions
Drug Drug Interaction
Interventions
First Posted Date
2023-07-20
Last Posted Date
2024-01-29
Lead Sponsor
Guangdong Raynovent Biotech Co., Ltd
Target Recruit Count
49
Registration Number
NCT05954624
Locations
🇨🇳

The First Affiliated Hospital of Guangzhou University of Chinese medicine, Guangzhou, China

A Drug Interaction Study Assess the Effects of ZSP1273 Tablets on the Pharmacokinetics of Warfarin and Midazolam

Phase 1
Completed
Conditions
Warfarin
Midazolam
Drug Drug Interaction
Interventions
First Posted Date
2023-07-12
Last Posted Date
2023-12-06
Lead Sponsor
Guangdong Raynovent Biotech Co., Ltd
Target Recruit Count
28
Registration Number
NCT05942365
Locations
🇨🇳

the Second Affiliated Hospital of Guangzhou Medical University, Guangzhou, China

Pharmacokinetics of ZSP1273 in Participants With Hepatic Impairment

Phase 1
Completed
Conditions
Hepatic Impairment
Pharmacokinetics
Interventions
First Posted Date
2023-05-12
Last Posted Date
2023-12-01
Lead Sponsor
Guangdong Raynovent Biotech Co., Ltd
Target Recruit Count
24
Registration Number
NCT05856513
Locations
🇨🇳

The First Hospital of Jilin University, Jilin, China

Study to Investigate the Potential Drug-Drug Interaction Between ZSP1273 and Oseltamivir

Phase 1
Completed
Conditions
Drug-drug Interaction
Interventions
First Posted Date
2021-11-04
Last Posted Date
2021-11-04
Lead Sponsor
Guangdong Raynovent Biotech Co., Ltd
Target Recruit Count
36
Registration Number
NCT05108051
Locations
🇨🇳

Guangdong Provincial Hospital of Chinese Medicine, Guangzhou, Guangdong, China

The Safety, Tolerability and Pharmacokinetic Study of ZSP1273 in Healthy Volunteers.

Phase 1
Completed
Conditions
Influenza
Interventions
Drug: ZSP1273 High Dose
Drug: ZSP1273 900 mg
Drug: ZSP1273 100 mg
Drug: ZSP1273 200 mg
Drug: ZSP1273 400 mg
Drug: ZSP1273 600 mg
Drug: ZSP1273 1200 mg
Drug: ZSP1273 Low Dose
Drug: ZSP1273 Median Dose
Drug: Placebo 1200 mg
Drug: Placebo 600 mg
Drug: Placebo
Drug: Placebo 200 mg
Drug: Placebo 400 mg
Drug: Placebo 900 mg
Drug: Placebo 100 mg
First Posted Date
2018-09-20
Last Posted Date
2019-08-14
Lead Sponsor
Guangdong Zhongsheng Pharmaceutical Co., Ltd.
Target Recruit Count
103
Registration Number
NCT03679143
Locations
🇨🇳

The First Hospital of Jilin University, Changchun, Jilin, China

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