Domperidone
- Generic Name
- Domperidone
- Brand Names
- -
- Drug Type
- Small Molecule
- Chemical Formula
- C22H24ClN5O2
- CAS Number
- 57808-66-9
- Unique Ingredient Identifier
- 5587267Z69
- Background
A specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
- Indication
For management of dyspepsia, heartburn, epigastric pain, nausea, and vomiting.
- Associated Conditions
- Diabetic Gastroparesis, Dyspepsia, Erosive Esophagitis, Gastrointestinal Symptoms, Non-erosive Reflux Esophagitis Disease (NERD), Upper gastrointestinal motility disorders
- Associated Therapies
- -
Treatment Use of Domperidone for Gastroparesis
- First Posted Date
- 2014-08-28
- Last Posted Date
- 2024-05-23
- Lead Sponsor
- Scott Gabbard, MD
- Registration Number
- NCT02227927
- Locations
- 🇺🇸
Cleveland Clinic, Cleveland, Ohio, United States
🇺🇸Cleveland Clinic Florida, Weston, Florida, United States
Gastroesophageal Reflux Treatment in Scleroderma
- First Posted Date
- 2013-06-17
- Last Posted Date
- 2017-03-27
- Lead Sponsor
- Khon Kaen University
- Target Recruit Count
- 80
- Registration Number
- NCT01878526
- Locations
- 🇹🇭
123 Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Domperidone for the Treatment of Chronic Nausea and Vomiting Secondary to Gastroparesis
- Conditions
- Interventions
- First Posted Date
- 2012-10-22
- Last Posted Date
- 2018-02-09
- Lead Sponsor
- Ron Schey
- Target Recruit Count
- 9
- Registration Number
- NCT01711918
- Locations
- 🇺🇸
University of Iowa Hospitals and Clinics, Iowa City, Iowa, United States
Domperidone in Treating Patients With Gastrointestinal Disorders
- First Posted Date
- 2012-10-01
- Last Posted Date
- 2024-08-02
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 200
- Registration Number
- NCT01696734
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
The Use of Domperidone for Gastroparesis
- First Posted Date
- 2011-06-23
- Last Posted Date
- 2013-03-19
- Lead Sponsor
- Allegiance Health
- Registration Number
- NCT01378884
Efficacy and Safety of Cinitapride Tablets in the Treatment of Mild to Moderate Functional Dyspepsia
- First Posted Date
- 2011-05-18
- Last Posted Date
- 2011-11-30
- Lead Sponsor
- Eisai China Inc.
- Target Recruit Count
- 400
- Registration Number
- NCT01355276
- Locations
- 🇨🇳
Wuxi People's Hospital, Wuxi, Jiangsu, China
🇨🇳Yangzhou First People's Hospital, Yangzhou, Jiangsu, China
🇨🇳Shanghai Changzheng Hospital, Shanghai, China
Symptomatic Treatment of Acute Gastroenteritis
- Conditions
- Interventions
- First Posted Date
- 2010-12-10
- Last Posted Date
- 2014-04-21
- Lead Sponsor
- IRCCS Burlo Garofolo
- Target Recruit Count
- 356
- Registration Number
- NCT01257672
- Locations
- 🇮🇹
Dipartimento di Emergenza Pediatrica, Ospedale Giuseppe Moscati, Avellino, Italy
🇮🇹Dipartimento di Emergenza Pediatrica, P.O. Spedali Civili, Brescia, Italy
🇮🇹Dipartimento di Pediatria, Ospedale Castelli, Verbania, Novara, Italy
The Effect of Acupuncture on Symptoms, Gastric Emptying Rate and Glucose Control in Patients With Diabetic Gastroparesis
- Conditions
- Interventions
- First Posted Date
- 2009-04-02
- Last Posted Date
- 2013-12-06
- Lead Sponsor
- Rabin Medical Center
- Target Recruit Count
- 8
- Registration Number
- NCT00874133
Domperidone for Refractory Gastrointestinal Disorders
- First Posted Date
- 2008-10-22
- Last Posted Date
- 2016-08-18
- Lead Sponsor
- Arnold, George, M.D.
- Target Recruit Count
- 75
- Registration Number
- NCT00777439
- Locations
- 🇺🇸
Division of Gastroenterology, Hepatology and Nutrition, UPMC Presbyterian Digesive Disorders Center, 3rd Floor, 200 Lothrop Street, Pittsburgh, Pennsylvania, United States
Domperidone for Relief of Gastrointestinal Disorders
- Conditions
- First Posted Date
- 2008-09-29
- Last Posted Date
- 2012-09-13
- Lead Sponsor
- Carle Physician Group
- Target Recruit Count
- 42
- Registration Number
- NCT00761254
- Locations
- 🇺🇸
Carle Health Care Incorporated d/b/a Carle Physician Group, Urbana, Illinois, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.