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Inavolisib

Generic Name
Inavolisib
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C18H19F2N5O4
CAS Number
2060571-02-8
Unique Ingredient Identifier
L4C1UY2NYH
Background

Inavolisib (GDC-0077) is under investigation in clinical trial NCT03006172 (To Evaluate the Safety, Tolerability, and Pharmacokinetics of GDC-0077 Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer).

Associated Conditions
-
Associated Therapies
-
Clinical Trials
Related News

A Study Evaluating Single-agent Inavolisib and Inavolisib Plus Atezolizumab in PIK3CA-Mutated Cancers

Phase 1
Recruiting
Conditions
PIK3CA-Mutated Cancers
Interventions
Drug: Inavolisib
Drug: Atezolizumab
First Posted Date
2024-07-11
Last Posted Date
2025-01-03
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
40
Registration Number
NCT06496568
Locations
🇺🇸

Moores Cancer Center at UC San Diego Health, La Jolla, California, United States

🇺🇸

California Cancer Associates for Research & Excellence, Inc., San Marcos, California, United States

🇺🇸

Vanderbilt-Ingram Cancer Ctr, Nashville, Tennessee, United States

and more 5 locations

A Study to Evaluate the Efficacy and Safety of Inavolisib in Combination With Phesgo Versus Placebo in Combination With Phesgo in Participants With PIK3CA-Mutated HER2-Positive Locally Advanced or Metastatic Breast Cancer

Phase 3
Recruiting
Conditions
Metastatic Breast Cancer
Interventions
Drug: Inavolisib
Drug: Taxane-based Chemotherapy
Drug: Phesgo
Drug: Placebo
Drug: Optional Endocrine Therapy of Investigator's Choice
First Posted Date
2023-06-08
Last Posted Date
2024-12-31
Lead Sponsor
Hoffmann-La Roche
Target Recruit Count
230
Registration Number
NCT05894239
Locations
🇺🇸

Lawrence J. Ellison Institute for Transformative Medicine, Los Angeles, California, United States

🇺🇸

Dana Farber Cancer Institute, Boston, Massachusetts, United States

🇺🇸

Ellison Institute of Technology, Los Angeles, California, United States

and more 156 locations
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