Melatonin
- Generic Name
- Melatonin
- Brand Names
- Circadin, Slenyto, Melatonin Neurim
- Drug Type
- Small Molecule
- Chemical Formula
- C13H16N2O2
- CAS Number
- 73-31-4
- Unique Ingredient Identifier
- JL5DK93RCL
- Background
Melatonin is a biogenic amine that is found in animals, plants and microbes. Aaron B. Lerner of Yale University is credited for naming the hormone and for defining its chemical structure in 1958. In mammals, melatonin is produced by the pineal gland. The pineal gland is small endocrine gland, about the size of a rice grain and shaped like a pine cone (hence ...
- Indication
Used orally for jet lag, insomnia, shift-work disorder, circadian rhythm disorders in the blind (evidence for efficacy), and benzodiazepine and nicotine withdrawal. Evidence indicates that melatonin is likely effective for treating circadian rhythm sleep disorders in blind children and adults. It has received FDA orphan drug status as an oral medication for ...
- Associated Conditions
- Insomnia
- Associated Therapies
- -
Impact of Melatonin on IVF/ICSI Outcomes in Prospective Poor Responders
- Conditions
- Interventions
- First Posted Date
- 2016-12-15
- Last Posted Date
- 2016-12-15
- Lead Sponsor
- Assiut University
- Target Recruit Count
- 100
- Registration Number
- NCT02993588
- Locations
- 🇪🇬
Osama Abdalmageed, Assiut, Egypt
Effects of Melatonin to Reduce Nocturnal Hypertension in Patients With Neurogenic Orthostatic Hypotension
- Conditions
- Interventions
- First Posted Date
- 2016-11-15
- Last Posted Date
- 2019-06-12
- Lead Sponsor
- Lawson Health Research Institute
- Target Recruit Count
- 10
- Registration Number
- NCT02963181
- Locations
- 🇨🇦
University Hospital, London, Ontario, Canada
Melatonin for Prevention of Post- Operative Delirium Pilot Study Protocol
- First Posted Date
- 2016-09-16
- Last Posted Date
- 2016-09-16
- Lead Sponsor
- Loyola University
- Registration Number
- NCT02903901
- Locations
- 🇺🇸
Loyola University Medical Center, Maywood, Illinois, United States
Pharmacokinetics of Melatonin Niosomes Oral Gel in Healthy Volunteers
- First Posted Date
- 2016-07-27
- Last Posted Date
- 2016-07-27
- Lead Sponsor
- Khon Kaen University
- Target Recruit Count
- 15
- Registration Number
- NCT02845778
- Locations
- 🇹🇭
Academic Clinical Research Office, Amphur Muang, Khon Kaen, Thailand
Multiple Dose Study Of BIIB118 (PF-05251749) In Healthy Volunteers
- Conditions
- Interventions
- First Posted Date
- 2016-02-25
- Last Posted Date
- 2021-02-17
- Lead Sponsor
- Biogen
- Target Recruit Count
- 97
- Registration Number
- NCT02691702
- Locations
- 🇺🇸
QPS-MRA, LLC (Miami Research Associates), South Miami, Florida, United States
🇺🇸Qps-Mra, Llc, South Miami, Florida, United States
Melatonin's Effects on Treatment Of Diabetes Mellitus
- First Posted Date
- 2016-02-25
- Last Posted Date
- 2019-04-08
- Lead Sponsor
- Shiraz University of Medical Sciences
- Target Recruit Count
- 60
- Registration Number
- NCT02691897
- Locations
- 🇮🇷
Shahid Motahhari Clinic, Shiraz University of Medical Sciences, Shiraz, Fars, Iran, Islamic Republic of
Effect of Melatonin on Cardiometabolic Risk- FULL
- First Posted Date
- 2016-02-15
- Last Posted Date
- 2019-02-22
- Lead Sponsor
- Brigham and Women's Hospital
- Target Recruit Count
- 120
- Registration Number
- NCT02681887
- Locations
- 🇺🇸
Brigham and Women's Hospital, Boston, Massachusetts, United States
Effects of Melatonin in PCOS Women
- First Posted Date
- 2016-01-26
- Last Posted Date
- 2016-12-06
- Lead Sponsor
- Catholic University of the Sacred Heart
- Target Recruit Count
- 40
- Registration Number
- NCT02663570
- Locations
- 🇮🇹
Catholic university of Sacred Heart, Rome, Italy
Prevention of Delirium in Inpatients Utilizing Melatonin
- First Posted Date
- 2016-01-13
- Last Posted Date
- 2022-03-21
- Lead Sponsor
- Yale University
- Target Recruit Count
- 277
- Registration Number
- NCT02654314
- Locations
- 🇺🇸
Yale New Haven Hospital, Saint Raphael Campus, New Haven, Connecticut, United States
The Effect of Melatonin on Early Signs of Hypertension in Teenagers With Diabetes Mellitus Type 1
- First Posted Date
- 2016-01-01
- Last Posted Date
- 2016-01-01
- Lead Sponsor
- Sheba Medical Center
- Target Recruit Count
- 30
- Registration Number
- NCT02644590
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.