Carbachol

Generic Name
Carbachol
Brand Names
Carbastat, Miostat
Drug Type
Small Molecule
Chemical Formula
C6H15N2O2
CAS Number
462-58-8
Unique Ingredient Identifier
54Z8M50D6Q
Background

Carbamoylcholine, also known as carbachol, is a muscarinic agonist discovered in 1932. Carbamoylcholine was initially used as a treatment for migraines, induction of diuresis, and other parasympathetic effects.

Carbamoylcholine was granted FDA approval on 28 September 1972.

Indication

Carbamoylcholine is indicated to induce miosis for surgery and to reduce intraocular pressure elevations in the first 24 hours after cataract surgery.

Associated Conditions
Acute angle-closure glaucoma, Increased Intra Ocular Pressure (IOP), Open Angle Glaucoma (OAG)
Associated Therapies
-

Safety and Efficacy Study of BRIMOCHOL™, BRIMOCHOL™ F, and Carbachol in Subjects With Emmetropic Phakic and Pseudophakic Presbyopia

First Posted Date
2021-03-01
Last Posted Date
2022-10-17
Lead Sponsor
Visus Therapeutics
Target Recruit Count
81
Registration Number
NCT04774237
Locations
🇺🇸

Total Eye Care, PA, Memphis, Tennessee, United States

🇺🇸

Global Research Management, Inc., Glendale, California, United States

🇺🇸

Eye Research Foundation, Newport Beach, California, United States

Carbachols Headache-inducing Effect and Changes in Cerebral Blood Flow in Migraine Patients

Not Applicable
Completed
Conditions
Interventions
First Posted Date
2007-11-28
Last Posted Date
2009-08-03
Lead Sponsor
Danish Headache Center
Target Recruit Count
12
Registration Number
NCT00564408
Locations
🇩🇰

Danish Headache Center, Glostrup, Denmark

Carbachol´s Headache Inducing Characteristics and Effects on the Cerebral Blood Flow

Completed
Conditions
First Posted Date
2006-07-28
Last Posted Date
2007-08-30
Lead Sponsor
Danish Headache Center
Target Recruit Count
15
Registration Number
NCT00357864
Locations
🇩🇰

Dansih Headache Center, Glostrup, Denmark

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