Tropicamide

Generic Name: Tropicamide

Brand Names: Minims Tropicamide, Mydcombi, Mydriacyl, Paremyd

Drug Type: Small Molecule

Chemical Formula: C_₁₇H_₂₀N_₂O_₂

CAS Number: 1508-75-4

Unique Ingredient Identifier: N0A3Z5XTC6

Background: Tropicamide is an alkaloid atropine‐derived anticholinergic drug and a non‐selective antagonist of muscarinic acetylcholine (mACh) receptors. Usually available in ophthalmic formulations, tropicamide is used to cause mydriasis and cycloplegia for eye exams or ocular procedures. It is also used in combination with hydroxyamphetamine for the same indication. O...

Indication: Tropicamide is indicated to induce mydriasis (dilation of the pupil) for diagnostic procedures and in conditions where short-term pupil dilation is desired, either as monotherapy or in combination with hydroxyamphetamine or phenylephrine. It provides clinically significant mydriasis with partial cycloplegia.

Associated Conditions: -

Associated Therapies: Diagnostic procedures

Clinical Trials

Cycloplegic Refraction in Pediatric Patients With Esotropia

Phase 4

Recruiting

Conditions: Esotropia
Cycloplegia
Refractive Errors
Vision Disorders

Interventions: Drug: Cyclopentolate
Drug: Tropicamide

First Posted Date: 2023-10-11

Last Posted Date: 2023-10-11

Lead Sponsor: Islamic Hospital, Jordan

Target Recruit Count: 100

Registration Number: NCT06077682

Locations: 🇶🇦
Hamad Medical Corporation, Doha, Qatar
🇯🇴
Yarmouk University, Irbid, Jordan

Cycloplegic Refraction Among Children

Phase 4

Completed

Conditions: Cycloplegia

Interventions: Drug: Cyclopentolate
Drug: Tropicamide

First Posted Date: 2022-07-05

Last Posted Date: 2022-07-05

Lead Sponsor: Islamic Hospital, Jordan

Target Recruit Count: 55

Registration Number: NCT05442801

Locations: 🇯🇴
Islamic Hospital, Amman, Jordan

Wearing-Off Period of Pharmacological Dilation and Anisocoria

Phase 4

Completed

Conditions: Anisocoria

Interventions: Drug: Tropicamide
Drug: 1% Pilocarpine
Drug: Proparacaine Hydrochloride
Device: Tono pen AVIA
Device: VG4 Gonio
Device: Reichert phoropter

First Posted Date: 2022-02-14

Last Posted Date: 2023-03-07

Lead Sponsor: Prisma Health-Upstate

Target Recruit Count: 11

Registration Number: NCT05238233

Locations: 🇺🇸
Prisma Health, Greenville, South Carolina, United States

The Effect of Brimonidine

Phase 4

Completed

Conditions: Intraocular Pressure

Interventions: Drug: Brimonidine
Drug: Tropicamide
Drug: Phenylephrine Ophthalmic Product

First Posted Date: 2019-05-22

Last Posted Date: 2024-02-01

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 13

Registration Number: NCT03959176

Locations: 🇺🇸
Wake Forest Baptist Medical Center, Winston-Salem, North Carolina, United States

The Effect of Brimonidine on Intraocular Pressure When Dilating Routine Patients

Phase 1

Completed

Conditions: Intraocular Pressure

Interventions: Drug: Alphagan
Drug: Phenylephrine
Drug: Tropicamide

First Posted Date: 2017-05-04

Last Posted Date: 2018-08-09

Lead Sponsor: Wake Forest University Health Sciences

Target Recruit Count: 5

Registration Number: NCT03139708

Locations: 🇺🇸
Wake Forest Baptist Health Eye Center, Winston-Salem, North Carolina, United States

Subfoveal Choroidal Thickness After Surgery for Age-related Cataracts

Not Applicable

Completed

Conditions: Cataract

Interventions: Procedure: Femtosecond laser-assisted cataract surgery
Procedure: Conventional phacoemulsification cataract surgery
Drug: Tropicamide
Drug: Proparacaine hydrochloride

First Posted Date: 2016-09-09

Last Posted Date: 2016-09-09

Lead Sponsor: Sun Yat-sen University

Target Recruit Count: 40

Registration Number: NCT02895074

Locations: 🇨🇳
Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong, China

Descemet Endothelial Thickness Comparison Trial

Phase 4

Conditions: Keratoplasty
Grafting, Corneal
Transplantation, Cornea
Keratoplasty, Lamellar
Transplantation, Corneal

Interventions: Procedure: DSAEK
Procedure: DMEK
Device: Endoserter
Drug: Prednisolone
Drug: Ofloxacin
Drug: Tropicamide
Device: Jones Tube
Drug: Phenylephrine

First Posted Date: 2015-02-26

Last Posted Date: 2020-11-25

Lead Sponsor: Oregon Health and Science University

Target Recruit Count: 38

Registration Number: NCT02373137

Locations: 🇺🇸
Byers Eye Institute, Stanford University, Palo Alto, California, United States
🇺🇸
F. I. Proctor Foundation, University of California, San Francisco, San Francisco, California, United States
🇺🇸
Casey Eye Institute, Oregon Health & Science University, Portland, Oregon, United States

Clinical Investigation on the Blood Oxygenation at the Optic Nerve Head in Fabry Patients

Completed

Conditions: Fabry Disease

Interventions: Procedure: Contrast sensitivity measurement
Procedure: Slit Lamp assessment and intra-ocular pressure measurement
Procedure: Visual field testing
Procedure: Oxygen flow at the optic nerve head measurement
Drug: Tropicamide
Device: OSOME

First Posted Date: 2013-12-30

Last Posted Date: 2017-05-02

Lead Sponsor: Université de Montréal

Target Recruit Count: 8

Registration Number: NCT02023086

Locations: 🇨🇦
Universite de Montreal, Montreal, Quebec, Canada

Study of Myopia Prevention in Children With Low Concentration of Atropine

Phase 4

Conditions: Myopia

Interventions: Drug: atropine
Drug: tropicamide

First Posted Date: 2007-10-10

Last Posted Date: 2007-10-10

Lead Sponsor: Min-Sheng General Hospital

Target Recruit Count: 60

Registration Number: NCT00541177

Locations: 🇨🇳
Min-Sheng General Hospital, Tao-Yuan, Taiwan

Prev
1
Next

Drug Development Updates

Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.

© Copyright 2024. All Rights Reserved by MedPath

Home Terms & Conditions Privacy Policy