Prednisone
- Generic Name
- Prednisone
- Brand Names
- Deltasone, Rayos, Winpred
- Drug Type
- Small Molecule
- Chemical Formula
- C21H26O5
- CAS Number
- 53-03-2
- Unique Ingredient Identifier
- VB0R961HZT
- Background
A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.
Prednisone was granted FDA approval on 21 February 1955.
- Indication
Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.
- Associated Conditions
- Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
- Associated Therapies
- Palliative Treatment
Trial of R-GemOx Versus R-miniCHOP Regimen in First-line Treatment of Elderly Diffuse Large B Cell Lymphoma
- Conditions
- Diffuse Large B Cell Lymphoma
- Interventions
- First Posted Date
- 2016-05-10
- Last Posted Date
- 2019-01-03
- Lead Sponsor
- The First Affiliated Hospital with Nanjing Medical University
- Target Recruit Count
- 258
- Registration Number
- NCT02767674
- Locations
- 🇨🇳
Shandong Province Hospital, Jinan, Shandong, China
🇨🇳Tongji Medical College of HUST, Wuhan, Hubei, China
🇨🇳The first Affiliated Hospital Of Nanjing Medical University(JiangSu Province Hospital), NanJing, Jiangsu, China
The Dose Response of Prednisone on Biochemical and Clinical Makers in Adult Healthy Volunteers
- First Posted Date
- 2016-05-10
- Last Posted Date
- 2016-05-10
- Lead Sponsor
- Pfizer
- Target Recruit Count
- 37
- Registration Number
- NCT02767089
- Locations
- 🇺🇸
Jasper Clinic, Inc., Kalamazoo, Michigan, United States
Denosumab Plus Enzalutamide, Abiraterone and Prednisone Compared to Denosumab Plus Enzalutamide Alone for Men With Castrate Resistant Prostate Cancer (CRPC) With Bone Metastases
- Conditions
- Prostate Cancer
- Interventions
- First Posted Date
- 2016-05-02
- Last Posted Date
- 2019-11-08
- Lead Sponsor
- University of Hawaii
- Target Recruit Count
- 1
- Registration Number
- NCT02758132
- Locations
- 🇺🇸
University of Hawaii Cancer Center, Honolulu, Hawaii, United States
Effects of p38 Inhibitor AZD7624 in Corticosteroid Resistant Asthma
- Conditions
- Corticosteroid Resistant (CR) Asthmatics
- Interventions
- First Posted Date
- 2016-04-28
- Last Posted Date
- 2019-08-21
- Lead Sponsor
- National Jewish Health
- Target Recruit Count
- 2
- Registration Number
- NCT02753764
- Locations
- 🇺🇸
National Jewish Health, Denver, Colorado, United States
Chidamide Plus R-CHOP in Elderly DLBCL
- Conditions
- Diffuse Large B-cell Lymphoma
- Interventions
- First Posted Date
- 2016-04-28
- Last Posted Date
- 2017-11-14
- Lead Sponsor
- Ruijin Hospital
- Target Recruit Count
- 49
- Registration Number
- NCT02753647
- Locations
- 🇨🇳
Shanghai Ruijin Hospital, Shanghai, Shanghai, China
Reduced Chemotherapy in Low Risk DLBCL
- Conditions
- Diffuse Large B-cell Lymphoma
- Interventions
- First Posted Date
- 2016-04-27
- Last Posted Date
- 2022-12-05
- Lead Sponsor
- Ruijin Hospital
- Target Recruit Count
- 290
- Registration Number
- NCT02752815
- Locations
- 🇨🇳
Shanghai Ruijin Hospital, Shanghai, Shanghai, China
Perioperative Oral Steroids for Chronic Rhinosinusitis Without Polyps (CRSsNP)
- Conditions
- Endoscopic Sinus SurgeryOral SteroidsChronic Rhinosinusitis Without PolypsChronic Rhinosinusitis
- Interventions
- First Posted Date
- 2016-04-22
- Last Posted Date
- 2020-08-04
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 81
- Registration Number
- NCT02748070
- Locations
- 🇺🇸
Stanford University, Stanford, California, United States
A Study of Brentuximab Vedotin, Rituximab, and Dose Attenuated CHP in Elderly Patients With Diffuse Large B-Cell Lymphoma (DLBCL)
- Conditions
- Diffuse Large B-Cell Lymphoma
- Interventions
- First Posted Date
- 2016-04-12
- Last Posted Date
- 2024-08-06
- Lead Sponsor
- Patrick Reagan
- Target Recruit Count
- 24
- Registration Number
- NCT02734771
- Locations
- 🇺🇸
University of Virginia Cancer Center, Charlottesville, Virginia, United States
🇺🇸James P. Wilmot Cancer Institute, University of Rochester Medical Center, Rochester, New York, United States
A Phase 2 Study of Ruxolitinib With Chemotherapy in Children With Acute Lymphoblastic Leukemia
- Conditions
- Leukemia
- Interventions
- First Posted Date
- 2016-03-31
- Last Posted Date
- 2024-11-29
- Lead Sponsor
- Incyte Corporation
- Target Recruit Count
- 171
- Registration Number
- NCT02723994
- Locations
- 🇺🇸
Sinai Hospital of Baltimore, Baltimore, Maryland, United States
🇺🇸Childrens Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States
🇺🇸Texas Childrens Hospital, Houston, Texas, United States
Sequential, Related Donor Partial Liver Transplantation Followed by Bone Marrow Transplantation for Hepatocellular Carcinoma (HCC)
- Conditions
- Fibrolamellar Hepatocellular CarcinomaHepatocellular Carcinoma (Fibrolamellar Variant)Hepatocellular Carcinoma
- Interventions
- Procedure: living related donor partial liver transplantationRadiation: Total body irradiationProcedure: Bone marrow transplant from same donorDrug: CyclophosphamideDrug: MesnaDrug: FilgrastimDrug: TacrolimusDrug: mycophenolate mofetilDrug: PrednisoneDrug: Antithymocyte globulinDrug: fludarabine
- First Posted Date
- 2016-03-09
- Last Posted Date
- 2018-06-15
- Lead Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
- Registration Number
- NCT02702960
- Locations
- 🇺🇸
Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, Maryland, United States
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.