Prednisone

Generic Name
Prednisone
Brand Names
Deltasone, Rayos, Winpred
Drug Type
Small Molecule
Chemical Formula
C21H26O5
CAS Number
53-03-2
Unique Ingredient Identifier
VB0R961HZT
Background

A synthetic anti-inflammatory glucocorticoid derived from cortisone. It is biologically inert and converted to prednisolone in the liver.

Prednisone was granted FDA approval on 21 February 1955.

Indication

Prednisone is indicated as an anti-inflammatory or immunosuppressive drug for allergic, dermatologic, gastrointestinal, hematologic, ophthalmologic, nervous system, renal, respiratory, rheumatologic, infectious, endocrine, or neoplastic conditions as well as in organ transplant.

Associated Conditions
Acne Vulgaris, Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Acute Gouty Arthritis, Acute Leukemia, Aggressive Lymphoma, Allergic Bronchopulmonary Aspergillosis, Allergic Conjunctivitis (AC), Allergic Rhinitis (AR), Allergic corneal marginal ulcers, Alveolitis, Extrinsic Allergic, Ankylosing Spondylitis (AS), Aspiration Pneumonitis, Asthma, Atopic Dermatitis, Autoimmune Hepatitis, Bell's Palsy, Berylliosis, Bullous dermatitis herpetiformis, Chorioretinitis, Congenital Adrenal Hyperplasia (CAH), Congenital Hypoplastic Anemia, Contact Dermatitis, Disseminated tuberculosis, Drug hypersensitivity reaction, Edema of the cerebrum, Epicondylitis, Erythroblastopenia, Giant Cell Arteritis (GCA), Hypercalcemia of Malignancy, Idiopathic Pulmonary Fibrosis (IPF), Immune Thrombocytopenia (ITP), Iridocyclitis, Iritis, Keratitis, Leukemias, Loeffler's syndrome, Lymphoma, Meningitis caused by Mycobacterium Tuberculosis, Metastatic Castration-Resistant Prostate Cancer (mCRPC), Mycosis Fungoides (MF), Ocular Inflammation, Ophthalmia, Sympathetic, Optic Neuritis, Pain caused by Herpes zoster, Pemphigus, Pericarditis, Pneumocystis Jirovecii Pneumonia, Polymyalgia Rheumatica (PMR), Polymyositis, Posterior Uveitis, Primary adrenocortical insufficiency, Psoriatic Arthritis, Pure Red Cell Aplasia, Regional Enteritis, Relapsing Polychondritis, Rheumatoid Arthritis, Rheumatoid Arthritis, Juvenile, Secondary adrenocortical insufficiency, Secondary thrombocytopenia, Serum Sickness, Severe Seborrheic Dermatitis, Sjogren's Syndrome (SS), Solid Organ Transplant Rejection, Stevens-Johnson Syndrome, Systemic Lupus Erythematosus, Takayasu Arteritis, Thyroid Eye Disease, Thyroiditis, Thyrotoxicosis, Trichinosis, Ulcerative Colitis, Uveitis, Vasculitis, Acquired immune hemolytic anemia, Acute Bursitis, Acute Crohn's Disease (CD), Acute Multiple sclerosis exacerbation, Acute rheumatic carditis, Anterior eye segment inflammation, Exfoliative erythroderma, Fulminating Tuberculosis, Idiopathic Bronchiolitis obliterans with organizing pneumonia, Idiopathic eosinophilic pneumonias, Non-suppurative Thyroiditis, Severe Psoriasis, Subacute Bursitis, Symptomatic Sarcoidosis, Synovitis of osteoarthritis, Systemic Dermatomyositis, Varicella-zoster virus acute retinal necrosis
Associated Therapies
Palliative Treatment

Combination Chemotherapy in Treating Patients With Intermediate-Grade or Immunoblastic Non-Hodgkin's Lymphoma

First Posted Date
2004-06-30
Last Posted Date
2018-11-14
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
61
Registration Number
NCT00002565
Locations
🇺🇸

University of Texas - MD Anderson Cancer Center, Houston, Texas, United States

🇧🇷

Faculdade de Medicina do ABC, Sao Paulo, Brazil

🇨🇱

Clinica Alemana, Santiago, Chile

Vaccine Therapy Plus Sargramostim Following Chemotherapy in Previously Untreated Aggressive Non-Hodgkin's Lymphoma

Phase 2
Completed
Conditions
First Posted Date
2004-06-25
Last Posted Date
2023-09-07
Lead Sponsor
University of Nebraska
Registration Number
NCT00004197
Locations
🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

🇺🇸

Stanford University Medical Center, Stanford, California, United States

SWOG-9239 Reduction of Immunosuppression Plus Interferon Alfa and Combination Chemotherapy in Treating Patients With Malignant Tumors That Develop After Organ Transplant

First Posted Date
2004-06-22
Last Posted Date
2013-01-24
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
20
Registration Number
NCT00002657
Locations
🇺🇸

Providence Hospital - Southfield, Southfield, Michigan, United States

🇺🇸

CCOP - Dayton, Kettering, Ohio, United States

🇺🇸

Boston Medical Center, Boston, Massachusetts, United States

and more 83 locations

Combination Chemotherapy, Bone Marrow Transplantation, and Radiation Therapy in Treating Infants With Acute Lymphoblastic Leukemia

Phase 2
Completed
Conditions
First Posted Date
2004-06-16
Last Posted Date
2014-07-24
Lead Sponsor
Children's Oncology Group
Registration Number
NCT00002785
Locations
🇺🇸

Children's Hospital Los Angeles, Los Angeles, California, United States

🇺🇸

Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, United States

🇺🇸

Ireland Cancer Center, Cleveland, Ohio, United States

and more 30 locations

Combination Chemotherapy With or Without Prednisone in Treating Patients With Recurrent and/or Metastatic Kidney Cancer

Phase 2
Completed
Conditions
First Posted Date
2004-06-09
Last Posted Date
2016-05-12
Lead Sponsor
University of New Mexico
Target Recruit Count
35
Registration Number
NCT00003584
Locations
🇺🇸

University of New Mexico Cancer Research & Treatment Center, Albuquerque, New Mexico, United States

Mitoxantrone and Prednisone With or Without Leflunomide in Treating Patients With Stage IV Prostate Cancer

Phase 2
Completed
Conditions
First Posted Date
2004-06-04
Last Posted Date
2012-09-11
Lead Sponsor
Pfizer
Registration Number
NCT00004071
Locations
🇺🇸

St. Vincents Comprehensive Cancer Center, New York, New York, United States

🇺🇸

Comprehensive Cancer Care Specialists of Boca Raton, Boca Raton, Florida, United States

🇺🇸

Florida Cancer Specialists, Fort Myers, Florida, United States

Combination Chemotherapy With or Without Dexrazoxane in Treating Children With Hodgkin's Disease

First Posted Date
2004-05-26
Last Posted Date
2014-07-24
Lead Sponsor
Children's Oncology Group
Target Recruit Count
219
Registration Number
NCT00005578
Locations
🇺🇸

University of Mississippi Medical Center, Jackson, Mississippi, United States

🇺🇸

Hackensack University Medical Center, Hackensack, New Jersey, United States

🇺🇸

Simmons Cancer Center - Dallas, Dallas, Texas, United States

and more 60 locations

Combination Chemotherapy With or Without Rituximab in Treating Patients With Newly Diagnosed Non-Hodgkin's Lymphoma

Phase 3
Completed
Conditions
First Posted Date
2004-05-25
Last Posted Date
2023-12-27
Lead Sponsor
University of Nebraska
Registration Number
NCT00004112
Locations
🇺🇸

University of Nebraska Medical Center, Omaha, Nebraska, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

SWOG-9320 Combination Chemotherapy, Radiation Therapy, and Antiviral Therapy in Treating Patients With AIDS-Related Lymphoma

First Posted Date
2004-05-24
Last Posted Date
2013-01-24
Lead Sponsor
SWOG Cancer Research Network
Target Recruit Count
52
Registration Number
NCT00002571
Locations
🇺🇸

MBCCOP - University of South Alabama, Mobile, Alabama, United States

🇺🇸

USC/Norris Comprehensive Cancer Center, Los Angeles, California, United States

🇺🇸

Jonsson Comprehensive Cancer Center, UCLA, Los Angeles, California, United States

and more 82 locations

Combination Chemotherapy and Interferon Alfa With or Without Bone Marrow or Peripheral Stem Cell Transplantation in Treating Patients With Myeloma

First Posted Date
2004-05-21
Last Posted Date
2013-12-19
Lead Sponsor
Medical Research Council
Target Recruit Count
750
Registration Number
NCT00002599
Locations
🇬🇧

Leeds Teaching Hospital Trust, Leeds, England, United Kingdom

© Copyright 2024. All Rights Reserved by MedPath