Succimer
- Generic Name
- Succimer
- Brand Names
- Chemet
- Drug Type
- Small Molecule
- Chemical Formula
- C4H6O4S2
- CAS Number
- 304-55-2
- Unique Ingredient Identifier
- DX1U2629QE
- Background
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
- Indication
For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 µg/dL. May also be used to treat mercury or arsenic poisoning.
- Associated Conditions
- Arsenic Poisoning, Lead Poisoning, Mercury Poisoning, Blood lead levels above 45 mcg/dL Lead poisoning
- Associated Therapies
- -
The Individual Therapy for Patients With Wilson's Disease
- Conditions
- Interventions
- First Posted Date
- 2019-05-21
- Last Posted Date
- 2019-05-21
- Target Recruit Count
- 400
- Registration Number
- NCT03957720
- Locations
- 🇨🇳
econd Affiliated Hospital,Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Edetate Calcium Disodium or Succimer in Treating Patients With Acute Myeloid Leukemia or Myelodysplastic Syndrome Undergoing Chemotherapy
- Conditions
- Blast Phase Chronic Myelogenous Leukemia, BCR-ABL1 PositiveHigh Risk Myelodysplastic SyndromeMyeloproliferative NeoplasmRefractory Acute Myeloid LeukemiaSecondary Acute Myeloid LeukemiaAcute Myeloid LeukemiaAcute Myeloid Leukemia Arising From Previous Myelodysplastic SyndromeVery High Risk Myelodysplastic SyndromeChronic Myelogenous Leukemia, BCR-ABL1 PositiveMyelodysplastic Syndrome
- Interventions
- First Posted Date
- 2018-08-15
- Last Posted Date
- 2024-06-25
- Lead Sponsor
- M.D. Anderson Cancer Center
- Target Recruit Count
- 58
- Registration Number
- NCT03630991
- Locations
- 🇺🇸
M D Anderson Cancer Center, Houston, Texas, United States
Mercury Chelation to Treat Autism
- Conditions
- First Posted Date
- 2006-09-14
- Last Posted Date
- 2013-09-18
- Lead Sponsor
- National Institute of Mental Health (NIMH)
- Registration Number
- NCT00376194
- Locations
- 🇺🇸
National Institute of Mental Health (NIMH), 9000 Rockville Pike, Bethesda, Maryland, United States
Treatment of Lead-Exposed Children Trial
- First Posted Date
- 2006-06-21
- Last Posted Date
- 2018-04-05
- Target Recruit Count
- 780
- Registration Number
- NCT00342849
- Locations
- 🇺🇸
Kennedy Krieger Institute, Baltimore, Maryland, United States
🇺🇸University of Medicine and Dentistry of New Jersey, Newark, New Jersey, United States
🇺🇸Childrens Hospital, Columbus, Columbus, Ohio, United States
Randomized Study of Succimer (Dimercaptosuccinic Acid) on Growth of Lead-Poisoned Children
- Conditions
- First Posted Date
- 2000-02-25
- Last Posted Date
- 2005-06-24
- Target Recruit Count
- 175
- Registration Number
- NCT00004838
Drug Development Updates
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