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Succimer

Generic Name
Succimer
Brand Names
Chemet
Drug Type
Small Molecule
Chemical Formula
C4H6O4S2
CAS Number
304-55-2
Unique Ingredient Identifier
DX1U2629QE

Overview

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

Background

A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.

Indication

For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 µg/dL. May also be used to treat mercury or arsenic poisoning.

Associated Conditions

  • Arsenic Poisoning
  • Lead Poisoning
  • Mercury Poisoning
  • Blood lead levels above 45 mcg/dL Lead poisoning

Clinical Trials

Title
Posted
Study ID
Phase
Status
Sponsor
2025/02/06
Phase 2
Recruiting
2019/05/21
Early Phase 1
Recruiting
Second Affiliated Hospital, School of Medicine, Zhejiang University
2018/08/15
Phase 1
Recruiting
2013/12/23
Phase 1
Completed
U.S. Army Medical Research and Development Command
2009/06/18
Phase 1
Completed
2008/12/18
Phase 1
Completed
Southwest College of Naturopathic Medicine
2006/09/14
Phase 2
Withdrawn
2006/06/21
Phase 3
Completed
National Institute of Environmental Health Sciences (NIEHS)
2000/02/25
Not Applicable
Completed
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

FDA Drug Approvals

Approved Product
Manufacturer
NDC Code
Route
Strength
Effective Date
Recordati Rare Diseases, Inc.
55292-201
ORAL
100 mg in 1 1
1/11/2023
Theragnostics Inc
71083-0020
INTRAVENOUS
1 mg in 1 1
1/31/2024

EMA Drug Approvals

Approved Product
Authorization Holder
Status
Issued Date
No EMA approvals found for this drug.

HSA Drug Approvals

Approved Product
Manufacturer
Approval Number
Dosage Form
Strength
Approval Date
No HSA approvals found for this drug.

NMPA Drug Approvals

Approved Product
Company
Approval Number
Drug Type
Dosage Form
Approval Date
Dimercaptosuccinic Acid Capsules
国药准字H20074087
化学药品
胶囊剂
4/24/2022
Dimercaptosuccinic Acid Capsules
国药准字H20083389
化学药品
胶囊剂
4/24/2022
Dimercaptosuccinic Acid Capsules
国药准字H20051784
化学药品
胶囊剂
8/19/2024
Dimercaptosuccinic Acid Capsules
国药准字H10940167
化学药品
胶囊剂
8/19/2024

PPB Drug Approvals

Approved Product
Registration No.
Company
Licence No.
Strength
Registration Date
No PPB approvals found for this drug.

TGA Drug Approvals

Approved Product
ARTG ID
Sponsor
Registration Type
Status
Registration Date
RADPHARM DMSA powder for injection
14326
Global Medical Solutions Australia Pty Limited T/A Radpharm Scientific
Medicine
A
9/5/1991
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