D-Glutamine

Generic Name
D-Glutamine
Brand Names
Endari
Drug Type
Small Molecule
Chemical Formula
C5H10N2O3
CAS Number
5959-95-5
Unique Ingredient Identifier
63HB36CA2Y
Background

A non-essential amino acid present abundantly throughout the body and is involved in many metabolic processes. It is synthesized from glutamic acid and ammonia. It is the principal carrier of nitrogen in the body and is an important energy source for many cells.

Indication

Used for nutritional supplementation, also for treating dietary shortage or imbalance.

Used to reduce the acute complications of sickle cell disease in adult and pediatric patients 5 years of age and older .

Associated Conditions
Osteoporosis, Acute Complications of Sickle Cell Disease
Associated Therapies
-

Effects of Oral Care With Glutamine on Oral Health, Oral Flora and Incidence of Pneumonia After Neurosurgery With Microbiome Analysis

Phase 4
Recruiting
Conditions
Interventions
First Posted Date
2019-03-07
Last Posted Date
2023-04-27
Lead Sponsor
Yanzhao
Target Recruit Count
100
Registration Number
NCT03867214
Locations
🇨🇳

Xijing Hospital, Xi'an, China

Glutamine for the Prevention of Radiation Toxicity in Subjects Conserving Therapy

Phase 2
Terminated
Conditions
Interventions
First Posted Date
2013-12-16
Last Posted Date
2019-05-29
Lead Sponsor
University of Arkansas
Target Recruit Count
14
Registration Number
NCT02012608
Locations
🇺🇸

University of Arkansas for Medical Sciences, Little Rock, Arkansas, United States

Aza-SAHA-GBM With AutoSCT for Refractory Lymphoma

First Posted Date
2013-11-14
Last Posted Date
2020-01-27
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
61
Registration Number
NCT01983969
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Randomized Trial of Glutamine in Patients With Mucositis or Esophagitis

First Posted Date
2013-09-30
Last Posted Date
2022-06-15
Lead Sponsor
M.D. Anderson Cancer Center
Target Recruit Count
77
Registration Number
NCT01952847
Locations
🇺🇸

University of Texas MD Anderson Cancer Center, Houston, Texas, United States

Validity Study of Glutamine to Improve Cardiac Function in Cardiac Surgery

First Posted Date
2013-02-20
Last Posted Date
2014-05-28
Lead Sponsor
Yuejiang Liu
Target Recruit Count
33
Registration Number
NCT01794884
Locations
🇨🇳

Zhongda Hospital Southeast University, Nanjing, Jiangsu, China

Glutamine in Preventing Peripheral Neuropathy in Patients With Multiple Myeloma Receiving Bortezomib

First Posted Date
2013-02-05
Last Posted Date
2019-10-22
Lead Sponsor
Beth Faiman
Target Recruit Count
9
Registration Number
NCT01783522
Locations
🇺🇸

Cleveland Clinic Taussig Cancer Institute, Case Comprehensive Cancer Center, Cleveland, Ohio, United States

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