Botulinum toxin type B
- Generic Name
- Botulinum toxin type B
- Brand Names
- Myobloc
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 93384-44-2
- Unique Ingredient Identifier
- 0Y70779M1F
- Background
Neurotoxin produced by fermentation of clostridium botulinum type B. The protein exists in noncovalent association with hemagglutinin and nonhemagglutinin proteins as a neurotoxin complex. The neurotoxin complex is recovered from the fermentation process and purified through a series of precipitation and chromatography steps.
- Indication
For the treatment of patients with cervical dystonia to reduce the severity of abnormal head position and neck pain associated with cervical dystonia.
- Associated Conditions
- Cervical Dystonia, Chronic Sialorrhea
- Associated Therapies
- -
Pilot Study on Botulinum Toxin B as Treatment for Hidradenitis Suppurativa
- Conditions
- Interventions
- First Posted Date
- 2017-04-06
- Last Posted Date
- 2018-10-25
- Lead Sponsor
- University Hospital of North Norway
- Target Recruit Count
- 20
- Registration Number
- NCT03103074
- Locations
- 🇳🇴
University Hospital North Norway, Tromso, Norway
Open-Label and Single-Arm Study of MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adults
- First Posted Date
- 2015-11-20
- Last Posted Date
- 2021-07-13
- Lead Sponsor
- Supernus Pharmaceuticals, Inc.
- Target Recruit Count
- 187
- Registration Number
- NCT02610868
Myobloc Atrophy Study
- Conditions
- Interventions
- First Posted Date
- 2014-01-31
- Last Posted Date
- 2015-12-16
- Lead Sponsor
- Georgetown University
- Target Recruit Count
- 10
- Registration Number
- NCT02052024
- Locations
- 🇺🇸
Medstar Georgetown University Hospital, Washington, District of Columbia, United States
Efficacy and Safety Study of MYOBLOC® Followed by Open-Label Multiple-Treatment With MYOBLOC® in the Treatment of Troublesome Sialorrhea in Adult Subjects
- First Posted Date
- 2013-11-25
- Last Posted Date
- 2021-07-13
- Lead Sponsor
- Supernus Pharmaceuticals, Inc.
- Target Recruit Count
- 187
- Registration Number
- NCT01994109
"DOES MYOBLOC™ IMPROVE FUNCTIONAL HAND USE IN YOUNG CHILDREN WITH A HYPERTONIC UPPER EXTREMITY?"
- Conditions
- First Posted Date
- 2005-10-13
- Last Posted Date
- 2005-10-13
- Lead Sponsor
- Stanford University
- Target Recruit Count
- 10
- Registration Number
- NCT00238641
- Locations
- 🇺🇸
Stanford University, Stanford, California, United States
Randomized, Double-Blind, Placebo-Controlled, Parallel, Group Dose-Response, Study of E2014 in Patients WIth Spasmodic Torticollis
- Conditions
- First Posted Date
- 2005-09-14
- Last Posted Date
- 2014-03-10
- Lead Sponsor
- Eisai Co., Ltd.
- Target Recruit Count
- 133
- Registration Number
- NCT00165776
Drug Development Updates
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