Basiliximab
- Generic Name
- Basiliximab
- Brand Names
- Simulect
- Drug Type
- Biotech
- Chemical Formula
- -
- CAS Number
- 179045-86-4
- Unique Ingredient Identifier
- 9927MT646M
- Background
A recombinant chimeric (murine/human) monoclonal antibody (IgG1k) that functions as an immunosuppressive agent, specifically binding to and blocking the interleukin-2 receptor a-chain (IL-2R alpha, also known as CD25 antigen) on the surface of activated T-lymphocytes. It is a 144 kDa glycoprotein obtained from fermentation of an established mouse myeloma cel...
- Indication
For prophylactic treatment of kidney transplant rejection
- Associated Conditions
- Rejection Acute Renal
- Associated Therapies
- -
Stem Cell Transplantation for Patients With Multiple Myeloma
- Conditions
- Interventions
- First Posted Date
- 2012-02-03
- Last Posted Date
- 2024-01-29
- Lead Sponsor
- University of Chicago
- Target Recruit Count
- 15
- Registration Number
- NCT01526096
- Locations
- 🇺🇸
University of Chicago, Chicago, Illinois, United States
Thymoglobulin Induction in Kidney Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2010-11-11
- Last Posted Date
- 2010-11-11
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 40
- Registration Number
- NCT01239563
- Locations
- 🇬🇧
Oxford Transplant Centre, Churchill Hospital, Oxford, Oxfordshire, United Kingdom
🇬🇧University of Oxford, Oxford, Oxfordshire, United Kingdom
Campath, Calcineurin Inhibitor Reduction and Chronic Allograft Nephropathy
- Conditions
- Interventions
- First Posted Date
- 2010-05-10
- Last Posted Date
- 2020-04-02
- Lead Sponsor
- University of Oxford
- Target Recruit Count
- 852
- Registration Number
- NCT01120028
- Locations
- 🇬🇧
Oxford Radcliffe Hospitals NHS Trust, Oxford, Oxon, United Kingdom
🇬🇧University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom
🇬🇧University Hospitals Coventry & Warwickshire, Coventry, United Kingdom
Basiliximab Maintenance in Ulcerative Colitis
- First Posted Date
- 2010-02-04
- Last Posted Date
- 2010-02-04
- Lead Sponsor
- Cerimon Pharmaceuticals
- Target Recruit Count
- 88
- Registration Number
- NCT01061996
Phase 3b Study to Evaluate Advagraf in Combination With Mycophenolate Mofetil and Basiliximab in Liver Transplantation
- Conditions
- Interventions
- First Posted Date
- 2009-11-11
- Last Posted Date
- 2024-11-01
- Lead Sponsor
- Astellas Pharma Inc
- Target Recruit Count
- 893
- Registration Number
- NCT01011205
- Locations
- 🇫🇮
026, Helsinki, Finland
🇧🇾146, Minsk, Belarus
🇧🇪006, Gent, Belgium
Basiliximab #2: In-Vivo Activated T-Cell Depletion to Prevent Graft-Versus_Host Disease (GVHD) After Nonmyeloablative Allotransplantation for the Treatment of Blood Cancer
- First Posted Date
- 2009-09-14
- Last Posted Date
- 2016-02-26
- Lead Sponsor
- Indiana University School of Medicine
- Target Recruit Count
- 17
- Registration Number
- NCT00975975
- Locations
- 🇺🇸
Indiana University Cancer Center, Indianapolis, Indiana, United States
Efficacy and Safety of Everolimus+EC-MPS After Early CNI Elimination vs EC-MPS +Tacrolimus in Renal Transplant Recipients
- Conditions
- Interventions
- First Posted Date
- 2009-08-25
- Last Posted Date
- 2014-08-15
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 36
- Registration Number
- NCT00965094
- Locations
- 🇮🇱
Novartis Investigative Site, Tel-Aviv, Israel
Study to Evaluate the Efficacy, Safety and Tolerability of Everolimus in de Novo Renal Transplant Recipients Participating in the Eurotransplant Senior Program
- Conditions
- Interventions
- First Posted Date
- 2009-08-11
- Last Posted Date
- 2014-06-06
- Lead Sponsor
- Novartis Pharmaceuticals
- Target Recruit Count
- 207
- Registration Number
- NCT00956293
- Locations
- 🇩🇪
Novartis Investigative Site, München, Germany
Study to Evaluate the Safety of Chronic Administration of Simulect to Subjects Receiving a First Kidney Transplant
- First Posted Date
- 2009-06-26
- Last Posted Date
- 2015-02-10
- Lead Sponsor
- Drexel University College of Medicine
- Target Recruit Count
- 5
- Registration Number
- NCT00928811
- Locations
- 🇺🇸
Drexel University College of Medicine, Philadelphia, Pennsylvania, United States
Safety and Effectiveness of Low Molecular Weight Sulfated Dextran in Islet Transplantation After Kidney Transplant
Drug Development Updates
Stay informed with timely notifications on clinical trials, regulatory changes, and research advancements related to this medication.