Marimastat

Generic Name
Marimastat
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C15H29N3O5
CAS Number
154039-60-8
Unique Ingredient Identifier
D5EQV23TDS
Background

Used in the treatment of cancer, Marmiastat is an angiogenesis and metastasis inhibitor. As an angiogenesis inhibitor it limits the growth and production of blood vessels. As an antimetatstatic agent it prevents malignant cells from breaching the basement membranes.

Indication

For the treatment of various cancers

Associated Conditions
-
Associated Therapies
-

Phase I Drug Trial for S/E of Marimastat in Disabling Malformations When no Other Options.

Phase 1
Completed
Conditions
First Posted Date
2005-12-05
Last Posted Date
2008-01-09
Lead Sponsor
Boston Children's Hospital
Target Recruit Count
9
Registration Number
NCT00261391
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Childrens Hospital, Boston, Massachusetts, United States

Marimastat in Treating Patients With Stage III Non-small Cell Lung Cancer

Phase 3
Completed
Conditions
First Posted Date
2004-05-26
Last Posted Date
2013-12-18
Lead Sponsor
ILEX Oncology Services, Incorporated
Registration Number
NCT00002911
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Hematology Associates, Ltd., Phoenix, Arizona, United States

๐Ÿ‡บ๐Ÿ‡ธ

Vincent T. Lombardi Cancer Research Center, Georgetown University, Washington, District of Columbia, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Connecticut Health Center, Farmington, Connecticut, United States

and more 47 locations

Marimastat or No Further Therapy in Treating Women With Metastatic Breast Cancer That Is Responding or Stable Following Chemotherapy

Phase 3
Completed
Conditions
First Posted Date
2004-04-14
Last Posted Date
2023-06-15
Lead Sponsor
Eastern Cooperative Oncology Group
Target Recruit Count
334
Registration Number
NCT00003010
Locations
๐Ÿ‡บ๐Ÿ‡ธ

CCOP - Carle Cancer Center, Urbana, Illinois, United States

๐Ÿ‡บ๐Ÿ‡ธ

Siouxland Hematology-Oncology, Sioux City, Iowa, United States

๐Ÿ‡บ๐Ÿ‡ธ

CCOP - Duluth, Duluth, Minnesota, United States

and more 22 locations

Marimastat Following Chemotherapy in Treating Patients With Small Cell Lung Cancer

Phase 3
Completed
Conditions
Interventions
First Posted Date
2004-02-16
Last Posted Date
2020-04-03
Lead Sponsor
NCIC Clinical Trials Group
Target Recruit Count
555
Registration Number
NCT00003011
Locations
๐Ÿ‡จ๐Ÿ‡ฆ

British Columbia Cancer Agency - Vancouver Island Cancer Centre, Victoria, British Columbia, Canada

๐Ÿ‡จ๐Ÿ‡ฆ

Cross Cancer Institute, Edmonton, Alberta, Canada

๐Ÿ‡จ๐Ÿ‡ฆ

British Columbia Cancer Agency, Vancouver, British Columbia, Canada

and more 35 locations
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