Methyl aminolevulinate

Generic Name
Methyl aminolevulinate
Brand Names
Metvix, Metvixia
Drug Type
Small Molecule
Chemical Formula
C6H11NO3
CAS Number
33320-16-0
Unique Ingredient Identifier
585NM85KYM
Background

Methyl aminolevulinate is a prodrug that is metabolised to Protoporphyrin IX (a photosensitizer) used in photodynamic therapy.

Indication

For topical use, in combination with 570 to 670 nm wavelength red light illumination, in the treatment of non-hyperkeratotic actinic keratoses of the face and scalp in immunocompetent patients when used in conjunction with lesion preparation (debridement using a sharp dermal curette).

Associated Conditions
Actinic Keratosis of Face and Scalp
Associated Therapies
-

Daylight Photodynamic Therapy for Actinic Keratosis and Skin Field Cancerization

Not Applicable
Conditions
Interventions
First Posted Date
2017-01-06
Last Posted Date
2017-01-06
Lead Sponsor
University of Sao Paulo General Hospital
Target Recruit Count
20
Registration Number
NCT03013647
Locations
🇧🇷

Hospital das Clinicas, Sao Paulo, SP, Brazil

Daylight PDT for Actinic Keratoses: a Multicentre Study Comparing Two Photosensitizers (BF-200 ALA Versus MAL)

First Posted Date
2015-06-08
Last Posted Date
2019-08-28
Lead Sponsor
Joint Authority for Päijät-Häme Social and Health Care
Target Recruit Count
72
Registration Number
NCT02464709
Locations
🇫🇮

Vaasa Central Hospital, Vaasa, Finland

🇫🇮

Tampere University Hospital, Tampere, Finland

🇫🇮

Päijät-Häme Central Hospital, Lahti, Finland

Trial of Methyl Aminolevulinate Plus Aktilite in Facial Photodamage

Phase 3
Completed
Conditions
Interventions
First Posted Date
2008-03-06
Last Posted Date
2009-03-16
Lead Sponsor
Universidad de Antioquia
Target Recruit Count
49
Registration Number
NCT00629317
Locations
🇨🇴

IPS Universitaria - Universidad de Antioquia, Medellin, Antioquia, Colombia

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