Tetracosactide

Generic Name
Tetracosactide
Brand Names
Cortrosyn, Synacthen
Drug Type
Small Molecule
Chemical Formula
C136H210N40O31S
CAS Number
16960-16-0
Unique Ingredient Identifier
72YY86EA29
Background

Tetracosactide (also known as Cosyntropin) is a synthetic peptide that is identical to the 24-amino acid segment (sequence: SYSMEHFRWGKPVGKKRRPVKVYP) at the N-terminal of adrenocorticotropic hormone. ACTH (1-24), a segment similar in all species, contains the biological activity that stimulates production of corticosteroids in the adrenal cortex. Tetracosact...

Indication

For use as a diagnostic agent in the screening of patients presumed to have adrenocortical insufficiency.

Associated Conditions
Acute Gouty Arthritis, Acute Rheumatic Fever, Adrenal Insufficiency, Ankylosing Spondylitis (AS), Bell's Palsy, Choroiditis, Conjunctivitis, Dermatomyositis (DM), Iritis, Keratitis, Lupus Erythematosus, Multiple sclerosis exacerbation, Nephrotic Syndrome, Ophthalmia, Sympathetic, Optic Neuritis, Panhypopituitarism, Pemphigus, Periarteritis nodosa, Psoriatic Arthritis, Rheumatoid Arthritis, Scleroderma, Still's Disease, Ulcerative Colitis, Uveitis, Acquired hemolytic jaundice, Exfoliative erythroderma
Associated Therapies
-

Study of the Approximate Entropy of Adrenocorticotropic Hormone and Cortisol Secretion in Patients With Head Injury

First Posted Date
2000-09-12
Last Posted Date
2005-06-24
Lead Sponsor
National Center for Research Resources (NCRR)
Target Recruit Count
32
Registration Number
NCT00006270
Locations
🇺🇸

Transitional Learning Community, Galveston, Texas, United States

🇺🇸

University of Texas Medical Branch, Galveston, Texas, United States

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