Patupilone

Generic Name
Patupilone
Brand Names
-
Drug Type
Small Molecule
Chemical Formula
C27H41NO6S
CAS Number
152044-54-7
Unique Ingredient Identifier
UEC0H0URSE
Background

Epothilone B is a 16-membered macrolide that mimics the biological effects of taxol.

Indication

Investigated for use/treatment in ovarian cancer, lung cancer, brain cancer, breast cancer, and gastric cancer.

Associated Conditions
-
Associated Therapies
-

Patupilone Activity in Advanced/Metastatic Hepatocellular Carcinoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2006-01-09
Last Posted Date
2017-02-07
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
25
Registration Number
NCT00273312
Locations
๐Ÿ‡จ๐Ÿ‡ณ

Novartis Investigative Site, Tai Chung Municipality, Taiwan

Study of Patupilone in Patients With Brain Metastasis From Non-small Cell Lung Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2005-09-22
Last Posted Date
2021-02-21
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
50
Registration Number
NCT00219297
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Roswell Park Cancer Institute, Buffalo, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

Cleveland Clinic Foundation, Cleveland, Ohio, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of California Davis Cancer Center UC Davis Cancer (3), Sacramento, California, United States

and more 9 locations

Dose Escalating Study of the Safety and Efficacy of Patupilone, q3w, in Patients With Non-small Cell Lung Cancer

Phase 1
Completed
Conditions
First Posted Date
2005-09-15
Last Posted Date
2014-02-05
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
89
Registration Number
NCT00171834
Locations
๐Ÿ‡บ๐Ÿ‡ธ

MD Anderson Cancer Center, Houston, Texas, United States

๐Ÿ‡บ๐Ÿ‡ธ

Ellis Fisher Cancer Center, Columbia, Missouri, United States

๐Ÿ‡บ๐Ÿ‡ธ

Hillman Cancer Center, Pittsburg, Pennsylvania, United States

and more 1 locations

EPO906 Therapy in Patients With Advanced Colorectal Cancer

Phase 2
Completed
Conditions
First Posted Date
2002-05-03
Last Posted Date
2013-12-04
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
62
Registration Number
NCT00035087
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Cancer Institute of New Jersey (CINJ), New Brunswick, New Jersey, United States

EPO906 Therapy in Patients With Advanced Melanoma

Phase 2
Completed
Conditions
Interventions
First Posted Date
2002-05-03
Last Posted Date
2012-04-25
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
51
Registration Number
NCT00035165
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Comprehensive Cancer Center@ Our Lady if Mercy Medical Center, Bronx, New York, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Colorado, Aurora, Colorado, United States

๐Ÿ‡บ๐Ÿ‡ธ

H. Lee Moffitt Cancer Center and Research Institute, Tampa, Florida, United States

and more 3 locations

EPO906 Therapy in Patients With Advanced Kidney Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2002-05-03
Last Posted Date
2012-04-17
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
53
Registration Number
NCT00035243
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Cleveland Clinic Foundation, Cleveland, Ohio, United States

๐Ÿ‡ซ๐Ÿ‡ท

Centre L. Berard, Lyon, France

๐Ÿ‡บ๐Ÿ‡ธ

UCLA Medical Center, Los Angeles, California, United States

and more 5 locations

EPO906 Therapy in Patients With Advanced Ovarian, Primary Fallopian, or Primary Peritoneal Cancer

First Posted Date
2002-05-03
Last Posted Date
2012-04-16
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
54
Registration Number
NCT00035100
Locations
๐Ÿ‡ฌ๐Ÿ‡ง

Novartis Investigative Site, Surrey, United Kingdom

EPO906 Therapy in Patients With Prostate Cancer

Phase 2
Completed
Conditions
First Posted Date
2002-05-03
Last Posted Date
2017-02-09
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
48
Registration Number
NCT00035113
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Pacific Shores Medical Group, Long Beach, California, United States

๐Ÿ‡บ๐Ÿ‡ธ

University of Maryland - Greenbaum Cancer Center, Baltimore, Maryland, United States

๐Ÿ‡บ๐Ÿ‡ธ

California Pacific Medical Center, San Francisco, California, United States

and more 2 locations

EPO906 Therapy in Patients With Advanced Breast Cancer

Phase 2
Completed
Conditions
Interventions
First Posted Date
2002-05-03
Last Posted Date
2017-02-08
Lead Sponsor
Novartis Pharmaceuticals
Target Recruit Count
46
Registration Number
NCT00035126
Locations
๐Ÿ‡บ๐Ÿ‡ธ

Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire, United States

๐Ÿ‡บ๐Ÿ‡ธ

Cancer Institute of New Jersey (CINJ), New Brunswick, New Jersey, United States

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